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ProNGF (Human) Proteins Molecular Depot
ProNGF (Human) Proteins Molecular Depot
ProNGF (Human) Proteins Molecular Depot
ProNGF (Human) Proteins Molecular Depot

ProNGF (Human)

$1,395.00

    Catalog Number: B2021792 (10 ug)

    ProNGF (Pro-Nerve Growth Factor) is a precursor protein to nerve growth factor (NGF). It plays a significant role in neurodevelopment and can bind to different receptors, inducing apoptosis in certain contexts. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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ProNGF (Human)

Catalog number: B2021792
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: ~25 kDa
Supplied as: Lyophiliized Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: Beta-NGF, Beta-nerve growth factor
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Barde, Y. A. (1990). Neurotrophins: a family of proteins supporting the survival of neurons. *Nature*, 349(6305), 529-531.
  • Lee, R., Kermani, P., Teng, K. K., & Hempstead, B. L. (2001). Neurotrophin-4/5 and proNGF: two distinct neurotrophic factors with opposing effects on neuronal survival. *Journal of Neuroscience*, 21(12), 4330-4340.
  • Nykjaer, A., & Willnow, T. E. (2012). A role for the sortilin receptor in the neurotrophic actions of proNGF. *Nature Reviews Neuroscience*, 13(11), 757-764.
  • Chao, M. V. (2003). Neurotrophins and their receptors: a convergence point for many signaling pathways. *Nature Reviews Neuroscience*, 4(4), 299-309.
  • Fahnestock, M., & Varon, S. (1995). The role of neurotrophins in the development and maintenance of the nervous system. *Journal of Neurobiology*, 26(4), 455-469.
  • Huang, E. J., & Reichardt, L. F. (2001). Neurotrophins: roles in neuronal development and function. *Annual Review of Neuroscience*, 24, 677-736.
  • Lee, R., & Chao, M. V. (2001). Activation of the Trk neurotrophin receptor by proNGF. *Journal of Biological Chemistry*, 276(29), 26788-26795.
  • Nykjaer, A., et al. (2004). Sortilin is essential for proNGF-induced neuronal cell death. *Nature*, 427(6975), 843-848.
  • Teng, K. K., et al. (2005). ProNGF induces neuronal apoptosis via a p75 neurotrophin receptor-dependent mechanism. *Journal of Neuroscience*, 25(12), 3092-3100.
  • Barde, Y. A., & Schneider, C. (1994). Neurotrophins: a family of proteins that promote the survival and differentiation of neurons. *Current Opinion in Neurobiology*, 4(5), 668-673.

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    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

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    By ordering, you waive all claims arising from use of Molecular Depot products.

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    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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