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Phospho-Stat5 (Tyr694) Rabbit PE Conjugate Proteins Molecular Depot
Phospho-Stat5 (Tyr694) Rabbit PE Conjugate Proteins Molecular Depot
Phospho-Stat5 (Tyr694) Rabbit PE Conjugate Proteins Molecular Depot
Phospho-Stat5 (Tyr694) Rabbit PE Conjugate Proteins Molecular Depot

Phospho-Stat5 (Tyr694) Rabbit PE Conjugate

$1,395.00

    Catalog Number: B2018649 (10 ug)

    Phospho-Stat5 (Tyr694) Rabbit PE Conjugate is a specific antibody for detecting phosphorylated Stat5 protein at tyrosine 694. It is conjugated to phycoerythrin (PE) for visualization and quantification of the phosphorylated protein in research on signaling pathways and protein phosphorylation events related to Stat5 activation. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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Phospho-Stat5 (Tyr694) Rabbit PE Conjugate

Catalog number: B2018649
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: Signal transducer and activator of transcription 5A, STAT5A, Signal transducer and activator of transcription 5B, STAT5B
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Beuvink I, Hess D, Flotow H, Hofsteenge J, Groner B, Hynes NE. Stat5a serine phosphorylation. Serine 779 is constitutively phosphorylated in the mammary gland, and serine 725 phosphorylation influences prolactin-stimulated in vitro DNA binding activity J Biol Chem. 2000 Apr 7;275(14):10247-55.
  • Gouilleux F, Wakao H, Mundt M, Groner B. Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription EMBO J. 1994 Sep 15;13(18):4361-9.
  • Altwaijry N, Sabour R, Ibrahim MH, Al Kamaly O, Abdullah O, Harras MF. Design, synthesis, and anti-hepatocellular carcinoma of thiopyrimidine/chalcone hybrids as dual STAT3/STAT5 inhibitors RSC Med Chem. 2023 Aug 15;14(10):1981-1991.
  • Spohn L, Fichter C, Werner M, Lassmann S. Subcellular localization of EGFR in esophageal carcinoma cell lines J Cell Commun Signal. 2016 Mar;10(1):41-7.
  • Adach A, Ellert-Miklaszewska A, Kaminska B. Molecular characterization of STAT signaling in inflammation and tumorigenesis Methods Mol Biol. 2009;512:265-78.
  • Zhao WL, Xing Y, Ye C, Qiu YH, Li Y, Liu XJ, Wang MY, Bi CW, Song DQ, Shao RG. The novel quinolizidine derivate IMB-HDC inhibits STAT5a phosphorylation at 694 and 780 and promotes DNA breakage and cell apoptosis via blocking STAT5a nuclear translocation Acta Pharmacol Sin. 2020 May;41(5):686-697.
  • Olayioye MA, Beuvink I, Horsch K, Daly JM, Hynes NE. ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases J Biol Chem. 1999 Jun 11;274(24):17209-18.
  • Chang M, Kanwar N, Feng E, Siu A, Liu X, Ma D, Jongstra J. PIM kinase inhibitors downregulate STAT3(Tyr705) phosphorylation Mol Cancer Ther. 2010 Sep;9(9):2478-87.
  • Sun Y, Cheng MK, Griffiths TR, Mellon JK, Kai B, Kriajevska M, Manson MM. Inhibition of STAT signalling in bladder cancer by diindolylmethane: relevance to cell adhesion, migration and proliferation Curr Cancer Drug Targets. 2013 Jan;13(1):57-68.

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    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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