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Native Canine Uromodulin Proteins Molecular Depot
Native Canine Uromodulin Proteins Molecular Depot
Native Canine Uromodulin Proteins Molecular Depot
Native Canine Uromodulin Proteins Molecular Depot

Native Canine Uromodulin

$1,995.00

    Catalog Number: B2016545 (2 μg)

    Native Canine Uromodulin is a high quality protein found in the urine of dogs. It is also known as Tamm-Horsfall protein and is primarily produced by the kidneys. Uromodulin plays a role in the formation of urine and may have protective effects on the urinary tract. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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Native Canine Uromodulin

Catalog number: B2016545
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 2 μg
Molecular Weight or Concentration: 5-kDa
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: Tamm-Horsfall urinary glycoprotein, THP, FJHN, HNFJ, THGP, MCKD2, ADMCKD2, UMOD, Uromodulin.
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Schweigert FJ, Raila J, Haebel S. Vitamin A excreted in the urine of canines is associated with a Tamm-Horsfall like protein Vet Res. 2002 May-Jun;33(3):299-311.
  • Seo D, Yang Y, Hwang SH, Jung JH, Cho S, Choi G, Kim Y. Serum uromodulin in dogs with chronic kidney disease J Vet Intern Med. 2022 Nov;36(6):2071-2078.
  • Nanamatsu A, Mori T, Ando F, Furusho T, Mandai S, Susa K, Sohara E, Rai T, Uchida S. Vasopressin Induces Urinary Uromodulin Secretion By Activating PKA (Protein Kinase A) Hypertension. 2021 Jun;77(6):1953-1963.
  • Rindler MJ, Naik SS, Li N, Hoops TC, Peraldi MN. Uromodulin (Tamm-Horsfall glycoprotein/uromucoid) is a phosphatidylinositol-linked membrane protein J Biol Chem. 1990 Dec 5;265(34):20784-9.
  • Gil da Costa RM, Oliveira JP, Saraiva AL, Seixas F, Faria F, Gärtner F, Pires MA, Lopes C. Immunohistochemical characterization of 13 canine renal cell carcinomas Vet Pathol. 2011 Mar;48(2):427-32.
  • Schaeffer C, Cattaneo A, Trudu M, Santambrogio S, Bernascone I, Giachino D, Caridi G, Campo A, Murtas C, Benoni S, Izzi C, De Marchi M, Amoroso A, Ghiggeri GM, Scolari F, Bachi A, Rampoldi L. Urinary secretion and extracellular aggregation of mutant uromodulin isoforms Kidney Int. 2012 Apr;81(8):769-78.
  • Bernascone I, Vavassori S, Di Pentima A, Santambrogio S, Lamorte G, Amoroso A, Scolari F, Ghiggeri GM, Casari G, Polishchuk R, Rampoldi L. Defective intracellular trafficking of uromodulin mutant isoforms Traffic. 2006 Nov;7(11):1567-79.
  • Kuleš J, Bilić P, Beer Ljubić B, Gotić J, Crnogaj M, Brkljačić M, Mrljak V. Glomerular and tubular kidney damage markers in canine babesiosis caused by Babesia canis Ticks Tick Borne Dis. 2018 Sep;9(6):1508-1517.
  • Bokhove M, Nishimura K, Brunati M, Han L, de Sanctis D, Rampoldi L, Jovine L. A structured interdomain linker directs self-polymerization of human uromodulin Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1552-7.

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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