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L-Selectin/CD62L Extracellular Domain Proteins Molecular Depot
L-Selectin/CD62L Extracellular Domain Proteins Molecular Depot
L-Selectin/CD62L Extracellular Domain Proteins Molecular Depot
L-Selectin/CD62L Extracellular Domain Proteins Molecular Depot

L-Selectin/CD62L Extracellular Domain

$1,795.00

    Catalog Number: B2016838 (50 µg)

    L-Selectin/CD62L Extracellular Domain is a high quality cell adhesion molecule that is expressed on the surface of leukocytes, including lymphocytes. It plays a key role in the immune response by mediating the adhesion of leukocytes to endothelial cells in the blood vessels, allowing them to migrate to sites of inflammation or infection. The extracellular domain of L-Selectin/CD62L refers to the portion of the protein that is located outside the cell membrane. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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All products are covered by manufacturer warranty

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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L-Selectin/CD62L Extracellular Domain

Catalog number: B2016838
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 61 kDa
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: CD62 Antigen-like Family Member L, LAM1, LECAM1, Leukocyte-endothelial Cell Adhesion Molecule 1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Stoddart JH Jr, Jasuja RR, Sikorski MA, von Andrian UH, Mier JW. Protease-resistant L-selectin mutants. Down-modulation by cross-linking but not cellular activation J Immunol. 1996 Dec 15;157(12):5653-9.
  • Spencer M, Max N, Ireland J, Zou Z, Wang R, Sun P. Over-expression of a human CD62L ecto-domain and a potential role of RNA pseudoknot structures in recombinant protein expression Protein Expr Purif. 2017 Dec;140:65-73.
  • Nishimura Y, Shimojima M, Tohya Y, Miyazawa T. Molecular cloning of a cDNA encoding the feline CD62L J Vet Med Sci. 2007 Jan;69(1):81-4.
  • Ivetic A, Hoskins Green HL, Hart SJ. L-selectin: A Major Regulator of Leukocyte Adhesion, Migration and Signaling Front Immunol. 2019 May 14;10:1068.
  • Drescher HK, Schippers A, Rosenhain S, Gremse F, Bongiovanni L, Bruin A, Eswaran S, Gallage SU, Pfister D, Szydlowska M, Heikenwalder M, Weiskirchen S, Wagner N, Trautwein C, Weiskirchen R, Kroy DC. L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men Cells. 2020 Apr 29;9(5):1106.
  • Golubovskaya V, Wu L. Different Subsets of T Cells, Memory, Effector Functions, and CAR-T Immunotherapy Cancers (Basel). 2016 Mar 15;8(3):36.
  • Segura J, He B, Ireland J, Zou Z, Shen T, Roth G, Sun PD. The Role of L-Selectin in HIV Infection Front Microbiol. 2021 Sep 29;12:725741.
  • Cichocki F, Zhang B, Wu CY, Chiu E, Day A, O’Connor RS, Yackoubov D, Simantov R, McKenna DH, Cao Q, Defor TE, Janakiram M, Wangen R, Cayci Z, Snyder N, Kumar A, Grzywacz B, Hwang J, Geffen Y, Miller JS, Maakaron J, Bachanova V. Nicotinamide enhances natural killer cell function and yields remissions in patients with non-Hodgkin lymphoma Sci Transl Med. 2023 Jul 19;15(705):eade3341.
  • Watson HA, Durairaj RRP, Ohme J, Alatsatianos M, Almutairi H, Mohammed RN, Vigar M, Reed SG, Paisey SJ, Marshall C, Gallimore A, Ager A. L-Selectin Enhanced T Cells Improve the Efficacy of Cancer Immunotherapy Front Immunol. 2019 Jun 12;10:1321.

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    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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