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Intrinsic Factor Biotinylated Proteins Molecular Depot
Intrinsic Factor Biotinylated Proteins Molecular Depot
Intrinsic Factor Biotinylated Proteins Molecular Depot
Intrinsic Factor Biotinylated Proteins Molecular Depot

Intrinsic Factor Biotinylated

$795.00

    Catalog Number: B2010612 (0.1 mg)

    Intrinsic Factor Biotinylated (0.1 mg) consists of a purified and concentrated solution of porcine Intrinsic Factor (IF) conjugated to biotin. IF is the natural binder and transporter of Vitamin B12, purified from the porcine gastric mucosa. This product has been used as a molecular tool in Vitamin B12 detection. This is supplied as a solution. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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    Email: info@bluetigerscientific.com

    Text/SMS: (833) 928-4437 Mon–Fri, (8 am – 8 pm PST)

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Intrinsic Factor Biotinylated (High Specificity)

Catalog number: B2010612
Lot number: Batch Dependent
Expiration date: Batch Dependent
Amount: 0.1 mg
Concentration: Not Available
Supplied as: Solution
Appearance: Clear Solution
Storage: –20°C
Keywords: IF-Biotin, Biotinylated IF, Biotinylated Intrinsic Factor
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ·cm) and are filtered through 0.22 μm.

Intrinsic Factor Biotinylated is a high-specificity reagent designed for vitamin B12-targeted detection, metabolic profiling, and assay development. This conjugate consists of gastric intrinsic factor (GIF) covalently linked to biotin, forming a clear, stable solution suitable for ELISA, streptavidin-based capture systems, and receptor-ligand interaction studies. Supplied in 0.1 mg aliquots, this reagent supports a wide range of biochemical and diagnostic workflows involving cobalamin transport, autoimmune diagnostics, and nutritional biochemistry.

Intrinsic factor is essential for the absorption of vitamin B12 in the small intestine. It binds cobalamin with high affinity and facilitates its uptake via receptor-mediated endocytosis. The biotinylated format enables seamless integration into streptavidin-coated platforms, enhancing assay sensitivity and modularity. Researchers working in gastroenterology, hematology, and immunology rely on IF-biotin conjugates to study B12 deficiency, pernicious anemia, and antibody-mediated interference with IF function.

This reagent is particularly useful in screening platforms for intrinsic factor antibodies, evaluating B12 bioavailability, and developing targeted delivery systems. It enables precise tracking and quantification of IF–cobalamin interactions in vitro, with high specificity and minimal background interference. Compatible with manual and automated platforms, this conjugate offers robust performance across ELISA, biosensor calibration, and multiplex detection systems.

Key benefits:

  • Intrinsic factor conjugated to biotin for streptavidin-based capture and detection
  • Supports vitamin B12 metabolism, absorption studies, and autoimmune diagnostics
  • Clear, stable solution compatible with ELISA and multiplex platforms
  • Biotechnology grade; filtered through 0.22 μm membranes
  • Supplied in 0.1 mg aliquots; store at –20°C to maintain activity

Products are for in vitro research use only (RUO).

References

  • Andersen KJ, Schjønsby H. Intrinsic factor-mediated binding of cyanocobalamin to cholestyramine. J Pharm Sci. 1978 Nov;67(11):1626–1627.
  • Adamczyk M et al. Modulation of cyanocobalamin chemiluminescence by intrinsic factor. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3917–3921.
  • Herbert V. Intrinsic Factor. Gastroenterology. 1965 Aug;49:218–220.
  • Khitarov MZ. Castle’s intrinsic factor (literature review). Probl Gematol Pereliv Krovi. 1970 Mar;15(3):50–54.
  • Kapadia CR et al. Free intrinsic factor in the small intestine in man. Gastroenterology. 1976 May;70(5 Pt.1):704–706.
  • Smolka A, Donaldson RM Jr. Monoclonal antibodies to human intrinsic factor. Gastroenterology. 1990 Mar;98(3):607–614.
  • Wolff R. Progress in the study of the intrinsic factor. Expos Annu Biochim Med. 1967;28:27–52.
  • Vaillant C et al. Cellular localization of intrinsic factor in pancreas and stomach of the dog. Cell Tissue Res. 1990 Apr;260(1):117–122.
  • Chery C et al. Gastric intrinsic factor deficiency with combined GIF heterozygous mutations and FUT2 secretor variant. Biochimie. 2013 May;95(5):995–1001.
  • Schipperijn AJ. Intrinsic factor in human gastric juice. Tijdschr Gastroenterol. 1966;9(4):337–348.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    Limitation of Liability
    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

    Waiver of Claims
    By ordering, you waive all claims arising from use of Molecular Depot products.

    Shipping & Handling
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    Delivery Estimates All delivery timelines are estimates and not guaranteed. FedEx service levels are subject to operational delays, weather disruptions, and regional restrictions.

    FedEx Pickup Cutoff Orders submitted after the daily FedEx pickup window may not ship until the next available pickup day.

    Shipping Exceptions FedEx may impose restrictions or delays due to package size, weight, destination, or service availability. Blue Tiger Scientific is not liable for delays beyond our control.

    Weekend & Holiday Handling Orders placed on weekends or holidays will be processed on the next business day.

    Returns & Refunds
    Returns must be requested within 30 days through Blue Tiger Scientific. Refunds are only issued for shipping errors or verified defects, and processed within 45 business days if approved. Customers are responsible for return shipping costs unless otherwise stated. Refunds will exclude original shipping fees paid at checkout.

    Warranty Disclaimer
    All products are provided "as-is" with no warranties. Warranty issues are handled by the manufacturer.

    Safety Guidelines
    Always consult the product’s SDS. Products must not be ingested, inhaled, or come into contact with skin or eyes unless specified.

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    Quality System (MD Levels)
    Molecular Depot’s MD-Quality System includes:

    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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    Retention of Title
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    Intellectual Property
    No rights to manufacturing processes or IP are transferred. Blue Tiger Scientific is not liable for IP-related claims.

    Force Majeure
    Neither party is liable for delays or failures caused by uncontrollable events (e.g., weather, regulations, supply disruptions).

    Manufacturing Access
    Product purchase does not grant access to proprietary manufacturing documents or methods.

    Resale Prohibition
    Products cannot be resold without written approval from Molecular Depot LLC. Blue Tiger Scientific enforces this restriction.

    Governing Law
    Terms are governed by California and U.S. law. All disputes fall under U.S. jurisdiction.

Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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