Inosine 5′-Monophosphate Disodium – Catalog Number: B2010680 (1 g)

Inosine 5′-Monophosphate (IMP) Disodium is supplied as a biotechnology-grade powder in a defined 1 g amount (Catalog B2010680) with a listed molecular weight of 392.17 g/mol and storage at RT. The supplier notes that this material is used as a molecular tool in the formulation of a wide variety of reagents, and it appears across biochemical and immunological research settings where a clearly specified IMP source is needed for method setup, controls, and exploratory studies. The concise specification set—amount, form, molecular weight, storage, and keyword identity—supports straightforward SOP documentation and inventory traceability in multi-user labs.

As the disodium salt of inosine monophosphate, this nucleotide provides a defined ribonucleotide monophosphate backbone that is convenient for pilot titrations, buffer compatibility checks, and qualitative readouts during early method development. The powder presentation enables accurate mass-based dosing and flexible preparation of stocks in user-selected media, letting teams map signal windows and background behavior for their particular workflows. Because the listing does not prescribe working concentrations, good practice is to establish conditions empirically—starting with small-scale dilutions and documenting solvent, pH, final concentration, and time-at-temperature—so results are reproducible across runs, analysts, and instrument platforms.

Typical research scenarios include assembling internal references for comparative experiments, preparing control arms when IMP is relevant to the study design, and evaluating sample-handling variables that affect nucleotide stability. The biotechnology-grade note—solutions prepared with Type I ultrapure water and 0.22 µm filtration—aligns with expectations for low background during optimization. Within these research-only boundaries, this clearly specified IMP disodium offering functions as a practical, dependable component for laboratories standardizing nucleotide-related workflows.

Why researchers choose this product:

• Defined 1 g fill with listed 392.17 g/mol molecular weight for precise documentation
• Convenient powder format allows accurate mass-based dosing and flexible stock preparation
• Specified storage at RT simplifies day-to-day handling and inventory control
• Supplier-stated use as a molecular tool for reagent formulation and diverse research workflows
• Biotechnology-grade note (Type I water; 0.22 µm filtration for solutions) supports low background
• Keyword synonyms (e.g., 5′-IMP 2Na Hydrate) aid SOP/LIMS searchability

This product is for Research Use Only (RUO). It is not intended for diagnostic or therapeutic use.

References

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• 2: Bonagurio LP, Murakami AE, Moreira CA, Comar JF, Pozza PC. Dietary supplementation with inosine-5′-monophosphate improves the functional, energetic, and antioxidant status of liver and muscle growth in pigs Sci Rep. 2022 Jan 10;12(1):350.
• 3: Zhang YW, Zhang D, Sun H. [The basic functions of inosine 5′-monophosphate dehydrogenase and its application in drug discovery] Yao Xue Xue Bao. 2014 Mar;49(3):285-92.
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• 5: Lovászi M, Németh ZH, Gause WC, Beesley J, Pacher P, Haskó G. Inosine monophosphate and inosine differentially regulate endotoxemia and bacterial sepsis FASEB J. 2021 Nov;35(11):e21935.
• 6: Sosa M, Saha A, Giner-Sorolla A, Hadden E, Hadden JW. Immunopharmacologic properties of inosine 5′-methyl monophosphate (MIMP) Ann N Y Acad Sci. 1993 Jun 23;685:458-63.
• 7: Matsuishi M, Tsuji M, Yamaguchi M, Kitamura N, Tanaka S, Nakamura Y, Okitani A. Inosine-5′-monophosphate is a candidate agent to resolve rigor mortis of skeletal muscle Anim Sci J. 2016 Nov;87(11):1407-1412.
• 8: Watt JM, Graeff R, Potter BVL. Small Molecule CD38 Inhibitors: Synthesis of 8-Amino-N1-inosine 5′-monophosphate, Analogues and Early Structure-Activity Relationship Molecules. 2021 Nov 26;26(23):7165.
• 9: Signorelli KL, Hadden JW. T cell immunostimulation by methyl inosine 5′-monophosphate: application to infectious diseases Int Immunopharmacol. 2003 Aug;3(8):1177-86.
• 10: Zhang P, Fu L, Liu H, Huda NU, Zhu X, Han D, Jin J, Yang Y, Kim YS, Xie S. Effects of inosine 5′-monophosphate supplementation in high fishmeal and high soybean diets on growth, immune-related gene expression in gibel carp (Carassius auratus gibelio var. CAS Ⅲ), and its challenge against Aeromonas hydrophila infection Fish Shellfish Immunol. 2019 Mar;86:913-921. pubmed.ncbi.nlm.nih.gov