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Human TBK1 Active GST Tagged Proteins Molecular Depot
Human TBK1 Active GST Tagged Proteins Molecular Depot
Human TBK1 Active GST Tagged Proteins Molecular Depot
Human TBK1 Active GST Tagged Proteins Molecular Depot

Human TBK1 Active GST Tagged

$2,195.00

    Catalog Number: B2016566 (5 ug)

    Human TBK1 Active GST Tagged is a high quality form of the human TANK-binding kinase 1 (TBK1) enzyme that has been modified with a glutathione S-transferase (GST) tag for purification and detection purposes. TBK1 is a serine/threonine protein kinase that plays a role in various cellular processes, including immune response and inflammation. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

    Live Inquiry about this product via:

    Email: info@bluetigerscientific.com

    Text/SMS: (833) 928-4437 Mon–Fri, (8 am – 8 pm PST)

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All products are covered by manufacturer warranty

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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Human TBK1 Active GST Tagged

Catalog number: B2016566
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 ug
Molecular Weight or Concentration: ~105 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: −80°C
Keywords: FLJ11330, NAK, T2K
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Yu H, Yu W, Luo SS, Yang YJ, Liu FT, Zhang Y, Chen Y, Sun YM, Wu JJ. Association of the TBK1 mutation p.Ile334Thr with frontotemporal dementia and literature review Mol Genet Genomic Med. 2019 Mar;7(3):e547.
  • Yu N, Xu X, Qi G, Liu D, Chen X, Ran X, Jiang Z, Li Y, Mao H, Hu C. Ctenopharyngodon idella TBK1 activates innate immune response via IRF7 Fish Shellfish Immunol. 2018 Sep;80:521-527.
  • Lv Y, Deng H, Liu Y, Chang K, Du H, Zhou P, Mao H, Hu C. The tyrosine kinase SRC of grass carp (Ctenopharyngodon idellus) up-regulates the expression of IFN I by activating TANK binding kinase 1 Dev Comp Immunol. 2021 Jan;114:103834.
  • Kaukinen P, Sillanpää M, Nousiainen L, Melén K, Julkunen I. Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKε and TBK1 functions J Med Virol. 2013 Jan;85(1):71-82.
  • Runde AP, Mack R, S J PB, Zhang J. The role of TBK1 in cancer pathogenesis and anticancer immunity J Exp Clin Cancer Res. 2022 Apr 9;41(1):135.
  • Zhang C, Shang G, Gui X, Zhang X, Bai XC, Chen ZJ. Structural basis of STING binding with and phosphorylation by TBK1 Nature. 2019 Mar;567(7748):394-398.
  • Zhang Q, Liu S, Zhang CS, Wu Q, Yu X, Zhou R, Meng F, Wang A, Zhang F, Chen S, Wang X, Li L, Huang J, Huang YW, Zou J, Qin J, Liang T, Feng XH, Lin SC, Xu P. AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity Mol Cell. 2022 Dec 1;82(23):4519-4536.e7.
  • Banoth B, Cassel SL. Mitochondria in innate immune signaling Transl Res. 2018 Dec;202:52-68.
  • Lafont E, Draber P, Rieser E, Reichert M, Kupka S, de Miguel D, Draberova H, von Mässenhausen A, Bhamra A, Henderson S, Wojdyla K, Chalk A, Surinova S, Linkermann A, Walczak H. TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation Nat Cell Biol. 2018 Dec;20(12):1389-1399.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

    Purchase Orders
    Confirmed orders are final and may not be canceled or refunded unless authorized in writing.

    Limitation of Liability
    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

    Waiver of Claims
    By ordering, you waive all claims arising from use of Molecular Depot products.

    Shipping & Handling
    Shipping is calculated at checkout. A minimum 27% handling fee applies to each order.

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    Shipping Exceptions FedEx may impose restrictions or delays due to package size, weight, destination, or service availability. Blue Tiger Scientific is not liable for delays beyond our control.

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    Warranty Disclaimer
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    Quality System (MD Levels)
    Molecular Depot’s MD-Quality System includes:

    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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    Governing Law
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Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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