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Human COX-1 (mammalian expressed) Proteins Molecular Depot
Human COX-1 (mammalian expressed) Proteins Molecular Depot
Human COX-1 (mammalian expressed) Proteins Molecular Depot
Human COX-1 (mammalian expressed) Proteins Molecular Depot

Human COX-1 (mammalian expressed)

$2,795.00

    Catalog Number: B2016813 (2500 U)

    Human COX-1 (mammalian expressed) is a high quality enzyme that is expressed in mammals, including humans. It plays a key role in the production of prostaglandins, which are important signaling molecules involved in various physiological processes in the body. COX-1 is constitutively expressed in many tissues and is involved in maintaining normal physiological functions, such as protecting the stomach lining and regulating blood flow to the kidneys. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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    Email: info@bluetigerscientific.com

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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Human COX-1 (mammalian expressed)

Catalog number: B2016813
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 2500 U
Molecular Weight or Concentration: 66.8 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: Cyclooxygenase 1, PGHS-1, Prostaglandin Endoperoxide Synthase 1, Prostaglandin G/H Synthase 1, Prostaglandin H2 Synthase 1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Yoshimura H, Sekine S, Adachi H, Uematsu Y, Mitani A, Futaki N, Shimizu N. High levels of human recombinant cyclooxygenase-1 expression in mammalian cells using a novel gene amplification method Protein Expr Purif. 2011 Nov;80(1):41-6.
  • Hla T, Neilson K. Human cyclooxygenase-2 cDNA Proc Natl Acad Sci U S A. 1992 Aug 15;89(16):7384-8.
  • Gierse JK. Purification of recombinant human COX-1 and COX-2 Methods Mol Biol. 2010;644:21-9.
  • Shay AE, Diwakar BT, Guan BJ, Narayan V, Urban JF Jr, Prabhu KS. IL-4 up-regulates cyclooxygenase-1 expression in macrophages J Biol Chem. 2017 Sep 1;292(35):14544-14555.
  • Chang KH, Park JH, Chung HY, Hwang-Bo J, Lee HH, Kim DH, Soh Y, Chung IS. Enhanced expression of recombinant human cyclooxygenase 1 from stably-transfected Drosophila melanogaster S2 cells by dimethyl sulfoxide is mediated by up-regulation of nitric oxide synthase and transcription factor Kr-h1 Biotechnol Lett. 2012 Jul;34(7):1243-50.
  • Tacconelli S, Contursi A, Falcone L, Mucci M, D’Agostino I, Fullone R, Sacco A, Zucchelli M, Bruno A, Ballerini P, Dovizio M, Patrignani P. Characterization of cyclooxygenase-2 acetylation and prostanoid inhibition by aspirin in cellular systems Biochem Pharmacol. 2020 Aug;178:114094.
  • Chang KH, Lee JM, Hwang-Bo J, Yoo KH, Sohn BH, Yang JM, Chung IS. Expression of recombinant cyclooxygenase 1 in Drosophila melanogaster S2 cells transformed with human beta1,4-galactosyltransferase and Galbeta1,4-GlcNAc alpha2,6-sialyltransferase Biotechnol Lett. 2007 Dec;29(12):1803-9.
  • Xu Y, Phipps S, Turner MJ, Simmons DL. The N-terminus of COX-1 and its effect on cyclooxygenase-1 catalytic activity J Genet Genomics. 2010 Feb;37(2):117-23.
  • Richards JA, Petrel TA, Brueggemeier RW. Signaling pathways regulating aromatase and cyclooxygenases in normal and malignant breast cells J Steroid Biochem Mol Biol. 2002 Feb;80(2):203-12.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

    Purchase Orders
    Confirmed orders are final and may not be canceled or refunded unless authorized in writing.

    Limitation of Liability
    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

    Waiver of Claims
    By ordering, you waive all claims arising from use of Molecular Depot products.

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    Shipping is calculated at checkout. A minimum 27% handling fee applies to each order.

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    FedEx Pickup Cutoff Orders submitted after the daily FedEx pickup window may not ship until the next available pickup day.

    Shipping Exceptions FedEx may impose restrictions or delays due to package size, weight, destination, or service availability. Blue Tiger Scientific is not liable for delays beyond our control.

    Weekend & Holiday Handling Orders placed on weekends or holidays will be processed on the next business day.

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    Always consult the product’s SDS. Products must not be ingested, inhaled, or come into contact with skin or eyes unless specified.

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    Quality System (MD Levels)
    Molecular Depot’s MD-Quality System includes:

    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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    Product purchase does not grant access to proprietary manufacturing documents or methods.

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    Products cannot be resold without written approval from Molecular Depot LLC. Blue Tiger Scientific enforces this restriction.

    Governing Law
    Terms are governed by California and U.S. law. All disputes fall under U.S. jurisdiction.

Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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