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Human Cardiac Tropomyosin Proteins Molecular Depot
Human Cardiac Tropomyosin Proteins Molecular Depot
Human Cardiac Tropomyosin Proteins Molecular Depot
Human Cardiac Tropomyosin Proteins Molecular Depot

Human Cardiac Tropomyosin

$1,595.00

    Catalog Number: B2018434 (0.1 mg  )

    Human Cardiac Tropomyosin is a key regulatory protein involved in muscle fiber contraction, particularly in the heart. Tropomyosin plays a crucial role in regulating actin and myosin interaction, essential for heart muscle contraction and relaxation. It controls calcium ion binding to muscle fibers, triggering the contraction process. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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Human Cardiac Tropomyosin

Catalog number: B2018434
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Human Cardiac Tropomyosin
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Cai W, Xu D, Zeng C, Liao F, Li R, Lin Y, Zhao Y, Dong W, Wang Q, Yang H, Wen D, Gu J, Shentu W, Yu H, Zhang X, Wei J, Duan J. Modulating Lysine Crotonylation in Cardiomyocytes Improves Myocardial Outcomes Circ Res. 2022 Aug 19;131(5):456-472.
  • Doran MH, Rynkiewicz MJ, Rasicci D, Bodt SML, Barry ME, Bullitt E, Yengo CM, Moore JR, Lehman W. Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin J Gen Physiol. 2023 Mar 6;155(3):e202213267.
  • El-Mezgueldi M. Tropomyosin dynamics J Muscle Res Cell Motil. 2014 Aug;35(3-4):203-10.
  • Cummins P, McGurk B, Littler WA. Radioimmunoassay of human cardiac tropomyosin in acute myocardial infarction Clin Sci (Lond). 1981 Mar;60(3):251-9.
  • Matyushenko AM, Nefedova VV, Kochurova AM, Kopylova GV, Koubassova NA, Shestak AG, Yampolskaya DS, Shchepkin DV, Kleymenov SY, Ryabkova NS, Katrukha IA, Bershitsky SY, Zaklyazminskaya EV, Tsaturyan AK, Levitsky DI. Novel Mutation Glu98Lys in Cardiac Tropomyosin Alters Its Structure and Impairs Myocardial Relaxation Int J Mol Sci. 2023 Aug 2;24(15):12359.
  • Loong CK, Zhou HX, Chase PB. Persistence length of human cardiac α-tropomyosin measured by single molecule direct probe microscopy PLoS One. 2012;7(6):e39676.
  • McConnell M, Tal Grinspan L, Williams MR, Lynn ML, Schwartz BA, Fass OZ, Schwartz SD, Tardiff JC. Clinically Divergent Mutation Effects on the Structure and Function of the Human Cardiac_Tropomyosin Overlap Biochemistry. 2017 Jul 5;56(26):3403-3413.
  • Bing W, Knott A, Redwood C, Esposito G, Purcell I, Watkins H, Marston S. Effect of hypertrophic cardiomyopathy mutations in human cardiac muscle alpha -tropomyosin (Asp175Asn and Glu180Gly) on the regulatory properties of human cardiac troponin determined by in vitro motility assay J Mol Cell Cardiol. 2000 Aug;32(8):1489-98.
  • Vanburen P, Palmer BM. Cooperative activation of the cardiac myofilament: the pivotal role of tropomyosin Circulation. 2010 Jan 26;121(3):351-3.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

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    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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