Fetal Bovine Serum (Highly Pure)

High-quality FBS for consistent cell growth and assay performance. Fetal Bovine Serum (FBS) remains one of the most widely used supplements in cell culture due to its broad spectrum of growth factors, hormones, carrier proteins, lipids, and micronutrients. This highly pure FBS is intended for research workflows that require reliable support of mammalian cell proliferation and viability across routine maintenance, expansion, and experimental assays. Each lot is produced under controlled conditions and supplied with batch-dependent specifications to help laboratories maintain reproducibility from experiment to experiment.

In addition to cell culture supplementation, FBS is frequently used in diverse biochemical and immunological applications, including blocking agents for immunoassays, serum protein binding studies, metabolite transport assays, and as a component in enzyme or receptor activity buffers. The complex mixture of serum proteins (notably albumin) provides protective effects that stabilize labile molecules and buffer cells against shear and environmental stress, improving experimental robustness. This product is provided in a convenient research size for pilot studies and method development, and it integrates readily into standard media formulations or custom serum-containing blends used by academic, biotech, and industrial labs.

When optimizing experimental design, researchers often evaluate serum concentration, pre-treatment (e.g., heat-inactivation if required by the protocol), and downstream compatibility with analytical readouts. The batch-dependent nature of serum necessitates lot verification in sensitive workflows; accordingly, this product is offered with traceable lot information and storage guidance to preserve performance characteristics. Whether you are establishing a new cell line, scaling up production, or tuning assay conditions, this highly pure FBS offers dependable performance for RUO applications.

Why researchers choose this product:

• Supports robust cell growth and viability across a wide range of mammalian cell lines
• Broad utility beyond culture—useful in immunoassays, protein binding, and stabilization studies
• Lot-traceable and batch dependent to support reproducible RUO workflows
• Convenient research size for pilot runs and protocol optimization
• Biotechnology grade; prepared with Type I water and 0.22 μm filtration where applicable

Indication for Use:
This product is for Research Use Only (RUO). It is not intended for human or animal administration, diagnostic procedures, or therapeutic applications.

References:

• 1: van der Valk J. Fetal bovine serum-a cell culture dilemma Science. 2022 Jan 14;375(6577):143-144.
• 2: Weber T, Wagner K. Replacing fetal bovine serum (FBS) in research and testing ALTEX. 2021;38(1):163-164.
• 3: Tang WH, Wang CF, Liao YD. Fetal bovine serum albumin inhibits antimicrobial peptide activity and binds drug only in complex with α1-antitrypsin Sci Rep. 2021 Jan 14;11(1):1267.
• 4: Liu S, Yang W, Li Y, Sun C. Fetal bovine serum, an important factor affecting the reproducibility of cell experiments Sci Rep. 2023 Feb 2;13(1):1942.
• 5: Eggert S, Wiest J, Rosolowski J, Weber T. Practical workshop on replacing fetal bovine serum (FBS) in life science research: From theory into practice ALTEX. 2022;39(4):712-713.
• 6: Vultaggio-Poma V, Scussel Bergamin L, Falzoni S, Tarantini M, Giuliani AL, Sandonà D, Polverino De Laureto P, Di Virgilio F. Fetal bovine serum contains biologically available ATP Purinergic Signal. 2024 Feb;20(1):83-89.
• 7: Vicogne D, Houdou M, Garat A, Climer L, Lupashin V, Morelle W, Foulquier F. Fetal bovine serum impacts the observed N-glycosylation defects in TMEM165 KO HEK cells J Inherit Metab Dis. 2020 Mar;43(2):357-366.
• 8: Subiran C, Kristensen SG, Andersen CY. Umbilical cord blood-derived platelet-rich plasma: a clinically acceptable substitute for fetal bovine serum? Fertil Steril. 2021 Feb;115(2):336-337.
• 9: Zhang R, Zhang H, Chen B, Luan T. Fetal bovine serum attenuating perfluorooctanoic acid-inducing toxicity to multiple human cell lines via albumin binding J Hazard Mater. 2020 May 5;389:122109.
• 10: Versteegen RJ, Murray J, Doelger S. Animal welfare and ethics in the collection of fetal blood for the production of fetal bovine serum ALTEX. 2021;38(2):319-323.