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Collagenase Inhibitor Proteins Molecular Depot
Collagenase Inhibitor Proteins Molecular Depot
Collagenase Inhibitor Proteins Molecular Depot
Collagenase Inhibitor Proteins Molecular Depot

Collagenase Inhibitor

$1,595.00

    Catalog Number: B2019011 (1 mg)

    A collagenase inhibitor is an enzyme that breaks down collagen. It can help maintain the integrity of connective tissues and potentially improve healing. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

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Collagenase Inhibitor – Catalog #B2019011 (1 mg)

Catalog # B2019011
Lot # Batch dependent
Expiration Batch dependent
Amount 1 mg
Molecular Weight 453 g/mol
Supplied As Powder
Applications Molecular biology inhibitor of collagenase for biochemical and immunological use
Storage Room temperature
Keywords Isoamylphosphonyl-Glycyl-L-Prolyl-L-Alanine, dipotassium salt, collagenase inhibitor
Grade Biotechnology grade; made with Type I ultrapure water; 0.22 µm filtered

Specific collagenase inhibition for controlled extracellular matrix retention and enzyme studies. Collagenase Inhibitor (Catalog #B2019011) is a high-purity, lyophilized powder (1 mg) containing Isoamylphosphonyl-Glycyl-L-Prolyl-L-Alanine, dipotassium salt—a competitive inhibitor tailored to inactivate collagenase activity. This molecular tool supports experiments requiring precise modulation of collagen degradation, including tissue integrity studies, regenerative matrix assays, and enzyme kinetic validations in RUO research environments.

By introducing this inhibitor into collagenase-rich systems, researchers gain tightly controlled conditions for assessing proteolytic specificity, matrix stability, and tissue preservation. The inhibitor is especially useful in workflows such as assay development, mechanistic signaling studies, or as a stabilization step during sample prep where premature collagen breakdown would compromise data. Its customizable dosing ensures flexibility across assay formats, from in vitro digestion studies to protease inhibition screens.

Manufactured under biotechnology-grade standards, the product is prepared using ultrapure Type I water and is micro-filtered to ensure clean, reproducible performance. Convenient room-temperature storage allows easy integration into lab workflows. Whether administered in biochemical assays, immunological testing, or comparative studies with metalloproteinase inhibitors, this collagenase inhibitor delivers a reliable and traceable means to control experimental proteolysis.

Why researchers choose this product:

  • Targeted collagenase inhibition for controlled extracellular matrix modulation
  • High purity and specific active inhibitor enable precise dosing
  • Lyophilized format simplifies storage and dosing flexibility
  • Validated grade with ultrapure preparation ensures low background interference
  • Traceable batch information enhances reproducibility in RUO protocols

Indication for Use:
This product is for Research Use Only (RUO). It is not intended for therapeutic, diagnostic, or clinical application.

References:

  • de Almeida LGN, Thode H, Eslambolchi Y, Chopra S, Young D, Gill S, Devel L, Dufour A. Matrix Metalloproteinases: From Molecular Mechanisms to Physiology, Pathophysiology, and Pharmacology Pharmacol Rev. 2022 Jul;74(3):712-768.
  • Mondal S, Adhikari N, Banerjee S, Amin SA, Jha T. Matrix metalloproteinase-9 (MMP-9) and its inhibitors in cancer: A minireview Eur J Med Chem. 2020 May 15;194:112260.
  • Jabłońska-Trypuć A, Matejczyk M, Rosochacki S. Matrix metalloproteinases (MMPs), the main extracellular matrix (ECM) enzymes in collagen degradation, as a target for anticancer drugs J Enzyme Inhib Med Chem. 2016;31(sup1):177-183.
  • Mao S, Liu X, Xia W. Chitosan oligosaccharide-g-linalool polymer as inhibitor of hyaluronidase and collagenase activity Int J Biol Macromol. 2021 Jan 1;166:1570-1577.
  • Chang YC, Hahn RA, Gordon MK, Laskin JD, Gerecke DR. A type IV collagenase inhibitor, N-hydroxy-3-phenyl-2-(4-phenylbenzenesulfonamido) propanamide (BiPS), suppresses skin injury induced by sulfur mustard Toxicol Appl Pharmacol. 2020 Aug 15;401:115078.
  • Zhang Y, Fu Y, Zhou S, Kang L, Li C. A straightforward ninhydrin-based method for collagenase activity and inhibitor screening of collagenase using spectrophotometry Anal Biochem. 2013 Jun 1;437(1):46-8.
  • Laronha H, Carpinteiro I, Portugal J, Azul A, Polido M, Petrova KT, Salema-Oom M, Caldeira J, et al. Challenges in Matrix Metalloproteinases Inhibition Biomolecules. 2020 May 5;10(5):717.
  • Rashid ZA, Bardaweel SK. Novel Matrix Metalloproteinase-9 (MMP-9) Inhibitors in Cancer Treatment Int J Mol Sci. 2023 Jul 28;24(15):12133.
  • Kim HJ, Lee Y. Endogenous Collagenases Regulate Osteoclast Fusion Biomolecules. 2020 May 1;10(5):705.
  • Amar S, Fields GB. Potential clinical implications of recent matrix metalloproteinase inhibitor design strategies Expert Rev Proteomics. 2015;12(5):445-7.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

    Purchase Orders
    Confirmed orders are final and may not be canceled or refunded unless authorized in writing.

    Limitation of Liability
    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

    Waiver of Claims
    By ordering, you waive all claims arising from use of Molecular Depot products.

    Shipping & Handling
    Shipping is calculated at checkout. A minimum 27% handling fee applies to each order.

    Delivery Estimates All delivery timelines are estimates and not guaranteed. FedEx service levels are subject to operational delays, weather disruptions, and regional restrictions.

    FedEx Pickup Cutoff Orders submitted after the daily FedEx pickup window may not ship until the next available pickup day.

    Shipping Exceptions FedEx may impose restrictions or delays due to package size, weight, destination, or service availability. Blue Tiger Scientific is not liable for delays beyond our control.

    Weekend & Holiday Handling Orders placed on weekends or holidays will be processed on the next business day.

    Returns & Refunds
    Returns must be requested within 30 days through Blue Tiger Scientific. Refunds are only issued for shipping errors or verified defects, and processed within 45 business days if approved. Customers are responsible for return shipping costs unless otherwise stated. Refunds will exclude original shipping fees paid at checkout.

    Warranty Disclaimer
    All products are provided "as-is" with no warranties. Warranty issues are handled by the manufacturer.

    Safety Guidelines
    Always consult the product’s SDS. Products must not be ingested, inhaled, or come into contact with skin or eyes unless specified.

    Legal Use Compliance
    Products must not be used in violation of any law—local, state, federal, or international.

    Accuracy of Orders
    Customers are responsible for verifying all order details before submission.

    Changes or Cancellations
    All changes must be in writing and approved. Cancellations may result in fees for materials, labor, or third-party costs.

    Quality System (MD Levels)
    Molecular Depot’s MD-Quality System includes:

    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

    Delivery & Claims
    Orders may ship in parts. Claims for shortages or defects must be submitted within 2 days of receipt. Delivery dates are estimates only.

    Extended Payment Terms
    Payment is due within 30 days unless agreed otherwise. A 5% weekly penalty applies to late payments. Blue Tiger Scientific reserves discretion on payment application.

    Retention of Title
    Ownership remains with Blue Tiger Scientific or Molecular Depot LLC until payment is complete. Goods must be stored separately and labeled until paid in full.

    Intellectual Property
    No rights to manufacturing processes or IP are transferred. Blue Tiger Scientific is not liable for IP-related claims.

    Force Majeure
    Neither party is liable for delays or failures caused by uncontrollable events (e.g., weather, regulations, supply disruptions).

    Manufacturing Access
    Product purchase does not grant access to proprietary manufacturing documents or methods.

    Resale Prohibition
    Products cannot be resold without written approval from Molecular Depot LLC. Blue Tiger Scientific enforces this restriction.

    Governing Law
    Terms are governed by California and U.S. law. All disputes fall under U.S. jurisdiction.

Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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