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CML-BSA Proteins Molecular Depot
CML-BSA Proteins Molecular Depot
CML-BSA Proteins Molecular Depot
CML-BSA Proteins Molecular Depot

CML-BSA

$1,595.00

    Catalog Number: B2017296 (200 µg)

    CML-BSA stands for Carboxymethyl Lysine-Bovine Serum Albumin. It is a type of advanced glycation end product (AGE) formed when proteins or lipids become glycated due to exposure to sugars. CML-BSA is used in scientific studies to investigate the effects of AGEs on various biological processes, including aging and chronic diseases. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

    Live Inquiry about this product via:

    Email: info@bluetigerscientific.com

    Text/SMS: (833) 928-4437 Mon–Fri, (8 am – 8 pm PST)

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Manufacturer Warranty

All products are covered by manufacturer warranty

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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CML-BSA

Catalog number: B2017296
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 200 µg
Molecular Weight or Concentration: 69.3 kDa
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: Nε-(1-Carboxymethyl)-L-lysine – Bovine Serum Albumin, Nε-(1-Carboxymethyl)-L-lysine -BSA
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Lee J, Hyon JY, Min JY, Huh YH, Kim HJ, Lee H, Yun SH, Choi CW, Jeong Ha S, Park J, Chung YH, Jeong HG, Ha SK, Jung SK, Kim Y, Han EH. Mitochondrial carnitine palmitoyltransferase 2 is involved in N(ε)-(carboxymethyl)-lysine-mediated diabetic nephropathy Pharmacol Res. 2020 Feb;152:104600.
  • Koito W, Araki T, Horiuchi S, Nagai R. Conventional antibody against Nepsilon-(carboxymethyl)lysine (CML) shows cross-reaction to Nepsilon-(carboxyethyl)lysine (CEL): immunochemical quantification of CML with a specific antibody J Biochem. 2004 Dec;136(6):831-7.
  • Lo MC, Lu CI, Chen MH, Chen CD, Lee HM, Kao SH. Glycoxidative stress-induced mitophagy modulates mitochondrial fates Ann N Y Acad Sci. 2010 Jul;1201:1-7.
  • Lo MC, Chen MH, Lee WS, Lu CI, Chang CR, Kao SH, Lee HM. Nε-(carboxymethyl) lysine-induced mitochondrial fission and mitophagy cause decreased insulin secretion from β-cells Am J Physiol Endocrinol Metab. 2015 Nov 15;309(10):E829-39.
  • Miyahara Y, Ikeda S, Muroya T, Yasuoka C, Urata Y, Horiuchi S, Kohno S, Kondo T. Nepsilon-(Carboxymethyl)lysine induces gamma-glutamylcysteine synthetase in RAW264.7 cells Biochem Biophys Res Commun. 2002 Aug 9;296(1):32-40.
  • Lo MC, Chen MH, Hsueh YT, Kuo YT, Lee HM. Alpha-lipoic acid suppresses N(ε)-(carboxymethyl) lysine-induced epithelial mesenchymal transition in HK-2 human renal proximal tubule cells Free Radic Res. 2018 Dec;52(11-12):1387-1397.
  • Svistounov DN, Berg TJ, McCourt PA, Zykova SN, Elvevold KH, Nagai R, Horiuchi S, Smedsrod BH. Lack of recognition of Nepsilon-(carboxymethyl)lysine by the mouse liver reticulo-endothelial system: implications for pathophysiology Biochem Biophys Res Commun. 2003 Oct 3;309(4):786-91.
  • Chen Y, Niu W, Chao YC, He Z, Ding R, Wu F, Liang C. Alagebrium targets the miR-27b/TSP-1 signaling pathway to rescue N(ε)-carboxymethyl-lysine-induced endothelial dysfunction Am J Transl Res. 2019 Mar 15;11(3):1569-1580. eCollection 2019.
  • Tang SC, Chan LY, Leung JC, Cheng AS, Lin M, Lan HY, Lai KN. Differential effects of advanced glycation end-products on renal tubular cell inflammation Nephrology (Carlton). 2011 May;16(4):417-25.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

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    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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