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ASH1L Bromodomain Human Recombinant Proteins Molecular Depot
ASH1L Bromodomain Human Recombinant Proteins Molecular Depot
ASH1L Bromodomain Human Recombinant Proteins Molecular Depot
ASH1L Bromodomain Human Recombinant Proteins Molecular Depot

ASH1L Bromodomain Human Recombinant

$5,995.00

    Catalog Number: B2017249 (1 mg)

    ASH1L Bromodomain Human Recombinant is a high quality recombinant version of the bromodomain of the ASH1L protein, which is derived from human cells. ASH1L (Absent, Small, or Homeotic Discs 1-Like) is a gene that encodes a protein involved in chromatin modification and gene regulation. The bromodomain is a specific protein domain within ASH1L that recognizes and binds to acetylated lysine residues on histone tails, playing a crucial role in the regulation of gene expression by influencing chromatin structure. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

    Products are for in vitro research use only (RUO).

    Live Inquiry about this product via:

    Email: info@bluetigerscientific.com

    Text/SMS: (833) 928-4437 Mon–Fri, (8 am – 8 pm PST)

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Most items ship same day

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Manufacturer Warranty

All products are covered by manufacturer warranty

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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ASH1L Bromodomain Human Recombinant

Catalog number: B2017249
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 42 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: Absent Small and Homeotic Disks Protein 1 homolog, ASH1-like protein, Histone-lysine N-Methyltransferase ASH1L, Lysine N-Methyltransferase 2H
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Devoucoux M, Roques C, Lachance C, Lashgari A, Joly-Beauparlant C, Jacquet K, Alerasool N, Prudente A, Taipale M, Droit A, Lambert JP, Hussein SMI, Côté J. MRG Proteins Are Shared by Multiple Protein Complexes With Distinct Functions Mol Cell Proteomics. 2022 Jul;21(7):100253.
  • Pérez-Pena J, Páez R, Nieto-Jiménez C, Sánchez VC, Galan-Moya EM, Pandiella A, Győrffy B, Ocana A. Mapping Bromodomains in breast cancer and association with clinical outcome Sci Rep. 2019 Apr 5;9(1):5734.
  • Nakamura T, Blechman J, Tada S, Rozovskaia T, Itoyama T, Bullrich F, Mazo A, Croce CM, Geiger B, Canaani E. huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctions Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7284-9.
  • Yan Y, Tian M, Li M, Zhou G, Chen Q, Xu M, Hu Y, Luo W, Guo X, Zhang C, Xie H, Wu QF, Xiong W, Liu S, Guan JS. ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder Neuron. 2022 Apr 6;110(7):1156-1172.e9.
  • Zhang C, Xu L, Zheng X, Liu S, Che F. Role of Ash1l in Tourette syndrome and other neurodevelopmental disorders Dev Neurobiol. 2021 Mar;81(2):79-91.
  • Xie M, Zhang L, Han L, Huang L, Huang Y, Yang M, Zhang N. The ASH1L-AS1-ASH1L axis controls NME1-mediated activation of the RAS signaling in gastric cancer Oncogene. 2023 Nov;42(46):3435-3445.
  • Zhang T, Ren T, Lin H, Tong Y, Zhang J, Nie J, Zhu Y, Wang Y, Jin B, Zhang C, Chen T, He M. ASH1L contributes to oocyte apoptosis by regulating DNA damage Am J Physiol Cell Physiol. 2022 Oct 1;323(4):C1264-C1273.
  • Maritz C, Khaleghi R, Yancoskie MN, Diethelm S, Brülisauer S, Ferreira NS, Jiang Y, Sturla SJ, Naegeli H. ASH1L-MRG15 methyltransferase deposits H3K4me3 and FACT for damage verification in nucleotide excision repair Nat Commun. 2023 Jul 1;14(1):3892.
  • Qin L, Williams JB, Tan T, Liu T, Cao Q, Ma K, Yan Z. Deficiency of autism risk factor ASH1L in prefrontal cortex induces epigenetic aberrations and seizures Nat Commun. 2021 Nov 15;12(1):6589.

    Terms & Conditions

    Blue Tiger Scientific is an independent third-party distributor of select products manufactured by Molecular Depot LLC. By purchasing from bluetigerscientific.com, you (“the Customer”) agree to the following terms, adapted from Molecular Depot’s original conditions:

    Product Use & Eligibility
    Products are for in vitro research use only (RUO). They are not intended for human or animal use, diagnosis, therapy, resale to consumers, or residential delivery. Sales are limited to verified business addresses.

    Payment Terms
    All purchases are prepaid and non-refundable once confirmed. Pricing is in USD and subject to change without notice.

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    Blue Tiger Scientific and Molecular Depot LLC are not responsible for any damages resulting from product use or misuse.

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    By ordering, you waive all claims arising from use of Molecular Depot products.

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    Shipping is calculated at checkout. A minimum 27% handling fee applies to each order.

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    FedEx Pickup Cutoff Orders submitted after the daily FedEx pickup window may not ship until the next available pickup day.

    Shipping Exceptions FedEx may impose restrictions or delays due to package size, weight, destination, or service availability. Blue Tiger Scientific is not liable for delays beyond our control.

    Weekend & Holiday Handling Orders placed on weekends or holidays will be processed on the next business day.

    Returns & Refunds
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    Quality System (MD Levels)
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    MD 1000: Non-regulated use, no change notification

    MD 2000: Non-regulated use, limited change notification

    MD 3000: Regulated use, enhanced quality standards

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    Governing Law
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Product Resources:

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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