{"product_id":"n-octyl-beta-d-maltoside-om-99-highly-purified","title":"n-Octyl-β-D-maltoside (OM), \u003e99%, Highly Purified","description":"\u003cdiv style=\"max-width:1400px; margin:0 auto; padding:40px 20px; font-family:'Open Sans',sans-serif; font-weight:300; background:#fff; color:#333; font-size:0.95rem; box-sizing:border-box;\"\u003e\n  \u003cdiv style=\"display:flex; flex-direction:column; gap:20px;\"\u003e\n\u003ch2 style=\"margin:0; font-weight:600;\"\u003en-Octyl-β-D-maltoside (OM), \u0026gt;99%, Highly Purified – Catalog #B2025797\u003c\/h2\u003e\n\u003cp\u003en-Octyl-β-D-maltoside (OM; Catalog #B2025797) is a non-ionic detergent consisting of a maltose head group linked to an eight-carbon alkyl chain. Supplied as 1 g of highly purified (\u0026gt;99%) powder, it is used to extract membrane proteins from lipid bilayers while preserving their native structure, and to maintain them in solution during purification, structural studies, and reconstitution.\u003c\/p\u003e\n\u003cdiv style=\"overflow-x:auto; max-width:100%; margin-bottom:20px;\"\u003e\n\u003ctable style=\"width:100%; max-width:640px; border-collapse:collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eCatalog number:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eB2025797\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eLot number:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eBatch dependent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eExpiration Date:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eBatch dependent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eAmount:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003e1 g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003e\u0026gt;99%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eCAS number:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003e82494-08-4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eMolecular formula:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eC\u003csub\u003e20\u003c\/sub\u003eH\u003csub\u003e38\u003c\/sub\u003eO\u003csub\u003e11\u003c\/sub\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003e454.5 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eCritical micelle concentration:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003e~19.5–23.4 mM (~0.9–1.1% w\/v), buffer dependent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eSupplied as:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003ePowder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eMembrane protein solubilization and purification, crystallization, detergent exchange, reconstitution into proteoliposomes by dialysis\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eRoom temperature\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eKeywords:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003en-Octyl-β-D-maltoside, n-octyl-β-D-maltopyranoside, octyl maltoside, OM, β-OM, C8G2, alkyl maltoside detergent, non-ionic detergent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eGrade:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eBiotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity \u0026gt;18 MΩ-cm) and are filtered through 0.22 um.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eScientific Overview\u003c\/h3\u003e\n\u003cp\u003eAlkyl glycoside detergents were developed as gentle, non-ionic alternatives to ionic detergents for handling membrane proteins; the maltoside series came out of work to purify active, stable cytochrome c oxidase. Within the series, alkyl chain length sets the detergent's behavior. With a C8 chain, OM has a critical micelle concentration of roughly 20 mM, about one hundred times higher than n-dodecyl-β-D-maltoside (DDM, ~0.17 mM). That high CMC means OM monomers are removed quickly by dialysis, which is why short-chain alkyl maltosides are used to reconstitute membrane proteins into lipid vesicles.\u003c\/p\u003e\n\u003cp\u003eKey applications include:\u003c\/p\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003eSolubilization and purification of integral membrane proteins\u003c\/li\u003e\n\u003cli\u003eMembrane protein crystallization and detergent screening\u003c\/li\u003e\n\u003cli\u003eDetergent exchange from longer-chain maltosides\u003c\/li\u003e\n\u003cli\u003eReconstitution of membrane proteins into proteoliposomes by dialysis\u003c\/li\u003e\n\u003cli\u003eChiral surfactant in capillary electrophoresis\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eUsage \u0026amp; Handling Guidance\u003c\/h3\u003e\n\u003cp\u003eStore the powder tightly closed at room temperature. Prepare stock solutions (for example, 10% w\/v) in ultrapure water or buffer; OM is freely soluble in water. For solubilization, work at concentrations well above the CMC, and optimize the detergent-to-protein and detergent-to-lipid ratio for each target.\u003c\/p\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eWorking range:\u003c\/strong\u003e Above ~20 mM (~1% w\/v) for micelle formation; optimize for your protein.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRemoval:\u003c\/strong\u003e The high CMC allows efficient removal by dialysis or dilution.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSolutions:\u003c\/strong\u003e Filter stock solutions and store at 2–8°C for short-term use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eWhat You Get\u003c\/h3\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003e1 g of n-octyl-β-D-maltoside as a powder\u003c\/li\u003e\n\u003cli\u003e\u0026gt;99% purity for sensitive membrane protein work\u003c\/li\u003e\n\u003cli\u003eEnough material for detergent screening and multiple preparations\u003c\/li\u003e\n\u003cli\u003eFor research use only (RUO)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eWhy Researchers Choose It\u003c\/h3\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003eNon-ionic head group that is gentle on protein structure\u003c\/li\u003e\n\u003cli\u003eHigh CMC for straightforward removal and reconstitution\u003c\/li\u003e\n\u003cli\u003eSmaller micelles than long-chain maltosides such as DDM\u003c\/li\u003e\n\u003cli\u003eHigh purity to minimize interference in structural and functional studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eFrequently Asked Questions (FAQ)\u003c\/h3\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhat is the CMC of n-octyl-β-D-maltoside?\u003c\/strong\u003e\u003cbr\u003eApproximately 19.5–23.4 mM (about 0.9–1.1% w\/v), depending on buffer and salt conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow does OM compare with DDM?\u003c\/strong\u003e\u003cbr\u003eBoth are maltoside detergents. DDM has a C12 chain and a CMC near 0.17 mM, forming larger micelles that are hard to dialyze away. OM's C8 chain gives a far higher CMC and smaller micelles, so it is easier to remove but may be less stabilizing for some fragile proteins.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCan OM be removed by dialysis?\u003c\/strong\u003e\u003cbr\u003eYes. Its high CMC makes dialysis an effective removal method, which is useful for reconstituting proteins into liposomes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow should I store it?\u003c\/strong\u003e\u003cbr\u003eKeep the powder tightly closed at room temperature. Store prepared solutions at 2–8°C and use promptly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCan I get a COA or SDS?\u003c\/strong\u003e\u003cbr\u003eRequest a quote or contact us and we will provide available lot documentation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"margin-top:20px; font-weight:bold; color:#c8102e;\"\u003eThis product is for Research Use Only (RUO). It is not intended for diagnostic or therapeutic use in humans or animals.\u003c\/div\u003e\n\u003chr\u003e\n\u003ch4\u003eReferences\u003c\/h4\u003e\n\u003cul style=\"padding-left:0; margin:0; list-style:none;\"\u003e\n\u003cli style=\"display:flex; justify-content:space-between; align-items:flex-start; gap:12px; padding:8px 0; border-bottom:1px solid #eee;\"\u003e\n\u003cspan style=\"flex:1;\"\u003eRosevear P, VanAken T, Baxter J, Ferguson-Miller S. Alkyl glycoside detergents: a simpler synthesis and their effects on kinetic and physical properties of cytochrome c oxidase. \u003cem\u003eBiochemistry.\u003c\/em\u003e 1980;19(17):4108-4115.\u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1021\/bi00558a032\" target=\"_blank\" rel=\"noopener\" style=\"flex-shrink:0; margin-top:2px;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height:28px; width:auto;\"\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli style=\"display:flex; justify-content:space-between; align-items:flex-start; gap:12px; padding:8px 0; border-bottom:1px solid #eee;\"\u003e\n\u003cspan style=\"flex:1;\"\u003eVanAken T, Foxall-VanAken S, Castleman S, Ferguson-Miller S. Alkyl glycoside detergents: synthesis and applications to the study of membrane proteins. \u003cem\u003eMethods Enzymol.\u003c\/em\u003e 1986;125:27-35.\u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/S0076-6879(86)25005-3\" target=\"_blank\" rel=\"noopener\" style=\"flex-shrink:0; margin-top:2px;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height:28px; width:auto;\"\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli style=\"display:flex; justify-content:space-between; align-items:flex-start; gap:12px; padding:8px 0; border-bottom:1px solid #eee;\"\u003e\n\u003cspan style=\"flex:1;\"\u003eAlpes H, Apell HJ, Knoll G, Plattner H, Riek R. Reconstitution of Na⁺\/K⁺-ATPase into phosphatidylcholine vesicles by dialysis of nonionic alkyl maltoside detergents. \u003cem\u003eBiochim Biophys Acta.\u003c\/em\u003e 1988;946(2):379-388.\u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/0005-2736(88)90413-0\" target=\"_blank\" rel=\"noopener\" style=\"flex-shrink:0; margin-top:2px;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height:28px; width:auto;\"\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e","brand":"Molecular Depot","offers":[{"title":"Default Title","offer_id":52805452333354,"sku":"BTS-B2025797","price":585.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/B2025797.png?v=1790798117","url":"https:\/\/bluetigerscientific.com\/products\/n-octyl-beta-d-maltoside-om-99-highly-purified","provider":"Blue Tiger Scientific","version":"1.0","type":"link"}