{"product_id":"human-urokinase-type-plasminogen-activator-upa","title":"Human Urokinase-type Plasminogen Activator (UPA)","description":"\u003cdiv style=\"max-width: 1400px; margin: 0 auto; padding: 40px 20px; font-family: 'Open Sans', sans-serif; font-weight: 300; background: #fff; color: #333; font-size: 0.95rem; box-sizing: border-box;\"\u003e\n                                    \u003cdiv style=\"display: flex; flex-direction: column; gap: 20px;\"\u003e\n                                        \u003cp\u003e\u003cstrong\u003eHuman Urokinase-type Plasminogen Activator (UPA)\u003c\/strong\u003e\u003c\/p\u003e\n                                        \u003cdiv style=\"overflow-x: auto; max-width: 100%; margin-bottom: 20px;\"\u003e\n                                        \u003ctable style=\"width: 500px; border-collapse: collapse;\"\u003e\n                                            \u003ctbody\u003e\n                                            \u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eCatalog number:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e B2014314\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eLot number:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Batch Dependent\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eExpiration Date:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Batch dependent\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eAmount:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e 20 μg\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eMolecular Weight or Concentration:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e 46 kDa\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eSupplied as:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Powder\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e molecular tool for various biochemical applications\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e −20°C\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eKeywords:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e ATF, BDPLT5, PLAU, QPD, UPA, URK, Urokinase, u-PA\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eGrade:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity \u0026gt;18 MΩ-cm) and are filtered through 0.22 um.\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n                                            \u003c\/tbody\u003e\n                                        \u003c\/table\u003e\n                                        \u003c\/div\u003e\n\n                                        \u003chr\u003e\n                                        \u003ch4\u003eReferences\u003c\/h4\u003e\n                                        \n                \u003cul style=\"padding-left: 20px; margin: 0;\"\u003e\n                \u003cli\u003eDinesh P, Rasool M. uPA\/uPAR signaling in rheumatoid arthritis: Shedding light on its mechanism of action Pharmacol Res. 2018 Aug;134:31-39.\u003c\/li\u003e\n\u003cli\u003eDass K, Ahmad A, Azmi AS, Sarkar SH, Sarkar FH. Evolving role of uPA\/uPAR system in human cancers Cancer Treat Rev. 2008 Apr;34(2):122-36.\u003c\/li\u003e\n\u003cli\u003eSu SC, Lin CW, Yang WE, Fan WL, Yang SF. The urokinase-type plasminogen activator (uPA) system as a biomarker and therapeutic target in human malignancies Expert Opin Ther Targets. 2016;20(5):551-66.\u003c\/li\u003e\n\u003cli\u003eFang C, Zhong Z, Zhang T, Jia S, Ding X, Zhou W, Wang X. Human hair derived uPA loaded capsules with dual near-infrared (I and II biowindows) laser responsive capabilities for multi-effective thrombolysis therapy J Mater Chem B. 2020 Dec 21;8(47):10854-10866.\u003c\/li\u003e\n\u003cli\u003eDreymann N, Wuensche J, Sabrowski W, Moeller A, Czepluch D, Vu Van D, Fuessel S, Menger MM. Inhibition of Human Urokinase-Type Plasminogen Activator (uPA) Enzyme Activity and Receptor Binding by DNA Aptamers as Potential Therapeutics through Binding to the Different Forms of uPA Int J Mol Sci. 2022 Apr 28;23(9):4890.\u003c\/li\u003e\n\u003cli\u003eS El Salamouni N, Buckley BJ, Jiang L, Huang M, Ranson M, Kelso MJ, Yu H. Disruption of Water Networks is the Cause of Human\/Mouse Species Selectivity in Urokinase Plasminogen Activator (uPA) Inhibitors Derived from Hexamethylene Amiloride (HMA) J Med Chem. 2022 Feb 10;65(3):1933-1945.\u003c\/li\u003e\n\u003cli\u003eLakka SS, Bhattacharya A, Mohanam S, Boyd D, Rao JS. Regulation of the uPA gene in various grades of human glioma cells Int J Oncol. 2001 Jan;18(1):71-9.\u003c\/li\u003e\n\u003cli\u003eZhou W. Effect of adenovirusmediated uPA gene transduction on the fibrinolytic activity of human umbilical vein endothelial cells Mol Med Rep. 2014 Nov;10(5):2701-5.\u003c\/li\u003e\n\u003cli\u003eOhshita H, Tateno C. Propagation of Human Hepatocytes in uPA\/SCID Mice: Producing Chimeric Mice with Humanized Liver Methods Mol Biol. 2017;1506:91-100.\u003c\/li\u003e\n                \u003c\/ul\u003e\n                                    \u003c\/div\u003e\n                                \u003c\/div\u003e","brand":"Molecular Depot","offers":[{"title":"Default Title","offer_id":50513125409066,"sku":"BTS-B2014314","price":1095.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/B2014314.png?v=1755624937","url":"https:\/\/bluetigerscientific.com\/products\/human-urokinase-type-plasminogen-activator-upa","provider":"Blue Tiger Scientific","version":"1.0","type":"link"}