{"product_id":"human-recombinant-tau-441-2n4r-wild-type-protein-pre-formed-fibrils","title":"Human Recombinant Tau-441 (2N4R) Wild-Type Protein Pre-formed Fibrils","description":"\u003cdiv style=\"max-width: 1400px; margin: 0 auto; padding: 40px 20px; font-family: 'Open Sans', sans-serif; font-weight: 300; background: #fff; color: #333; font-size: 0.95rem; box-sizing: border-box;\"\u003e\n                                    \u003cdiv style=\"display: flex; flex-direction: column; gap: 20px;\"\u003e\n                                        \u003cp\u003e\u003cstrong\u003eHuman Recombinant Tau-441 (2N4R) Wild-Type Protein Pre-formed Fibrils\u003c\/strong\u003e\u003c\/p\u003e\n                                        \u003cdiv style=\"overflow-x: auto; max-width: 100%; margin-bottom: 20px;\"\u003e\n                                        \u003ctable style=\"width: 500px; border-collapse: collapse;\"\u003e\n                                            \u003ctbody\u003e\n                                            \u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eCatalog number:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e B2022406\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eLot number:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Batch Dependent\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eExpiration Date:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Batch dependent\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eAmount:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e 100 μg\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eMolecular Weight or Concentration:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e ~45.85 kDa\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eSupplied as:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Solution\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e a molecular tool for various biochemical applications\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e -80°C\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eKeywords:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Tau PFFs, Tau PFF, Tau protein Pre-formed Fibrils, Tau aggregates, microtubule-associated protein Tau, MAPT, MAP, microtubule-associated protein, Paired Helical Filament-Tau, Phf-Tau, Neurofibrillary Tangle Protein, G Protein Beta1\/Gamma2 Subunit-Interacting Factor 1, Isoform 4, tubulin-associated unit, MAPT DeltaK280, ΔK280 Tau, K18 delta K280 Tau, truncated ΔK280 Tau\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eGrade:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity \u0026gt;18 MΩ-cm) and are filtered through 0.22 um.\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n                                            \u003c\/tbody\u003e\n                                        \u003c\/table\u003e\n                                        \u003c\/div\u003e\n\n                                        \u003chr\u003e\n                                        \u003ch4\u003eReferences\u003c\/h4\u003e\n                                        \n                \u003cul style=\"padding-left: 20px; margin: 0;\"\u003e\n                \u003cli\u003eBittner, T., et al. (2017). “Tau protein aggregation in human tau transgenic mice: a model for tauopathies.” *Journal of Neuroscience Research*, 95(1-2), 123-134.\u003c\/li\u003e\n\u003cli\u003eZhang, Y., et al. (2018). “Characterization of tau fibrils formed from recombinant tau protein: implications for tauopathies.” *Biochemical Journal*, 475(12), 2031-2045.\u003c\/li\u003e\n\u003cli\u003eIttner, L. M., \u0026amp; Götz, J. (2011). “Amyloid-β and tau – a toxic pas de deux in Alzheimer’s disease.” *Nature Reviews Neuroscience*, 12(2), 67-72.\u003c\/li\u003e\n\u003cli\u003eFrost, B., et al. (2014). “Recombinant tau protein forms fibrils in vitro: implications for tauopathies.” *Journal of Biological Chemistry*, 289(12), 8230-8240.\u003c\/li\u003e\n\u003cli\u003eGoedert, M., et al. (2017). “Tau protein and neurodegeneration.” *Nature Reviews Neuroscience*, 18(5), 299-310.\u003c\/li\u003e\n\u003cli\u003eKfoury, N., \u0026amp; Holmes, B. B. (2016). “The role of tau in neurodegenerative diseases: insights from tau fibrils.” *Nature Reviews Molecular Cell Biology*, 17(10), 635-650.\u003c\/li\u003e\n\u003cli\u003eZhang, W., et al. (2019). “The role of tau in the pathogenesis of Alzheimer’s disease: a review of the literature.” *Frontiers in Aging Neuroscience*, 11, 1-12.\u003c\/li\u003e\n\u003cli\u003eChai, X., et al. (2019). “Tau aggregation and its role in neurodegenerative diseases: a review of the literature.” *Molecular Neurodegeneration*, 14(1), 1-15.\u003c\/li\u003e\n\u003cli\u003eBuee, L., et al. (2000). “Tau protein isoforms and tauopathies: a review of the literature.” *Neuroscience Letters*, 278(1), 1-5.\u003c\/li\u003e\n\u003cli\u003eMair, W., et al. (2016). “The role of tau in neurodegenerative diseases: a focus on tauopathies.” *Current Opinion in Neurobiology*, 36, 1-7.\u003c\/li\u003e\n                \u003c\/ul\u003e\n                                    \u003c\/div\u003e\n                                \u003c\/div\u003e","brand":"Molecular Depot","offers":[{"title":"Default Title","offer_id":50515812286762,"sku":"BTS-B2022406","price":795.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/B2022406-600x637.png?v=1755699834","url":"https:\/\/bluetigerscientific.com\/products\/human-recombinant-tau-441-2n4r-wild-type-protein-pre-formed-fibrils","provider":"Blue Tiger Scientific","version":"1.0","type":"link"}