{"product_id":"human-recombinant-tau-412-1n4r-wild-type-pre-formed-fibrils","title":"Human Recombinant Tau-412 (1N4R) Wild-Type Pre-formed Fibrils","description":"\u003cdiv style=\"max-width: 1400px; margin: 0 auto; padding: 40px 20px; font-family: 'Open Sans', sans-serif; font-weight: 300; background: #fff; color: #333; font-size: 0.95rem; box-sizing: border-box;\"\u003e\n                                    \u003cdiv style=\"display: flex; flex-direction: column; gap: 20px;\"\u003e\n                                        \u003cp\u003e\u003cstrong\u003eHuman Recombinant Tau-412 (1N4R) Wild-Type Pre-formed Fibrils\u003c\/strong\u003e\u003c\/p\u003e\n                                        \u003cdiv style=\"overflow-x: auto; max-width: 100%; margin-bottom: 20px;\"\u003e\n                                        \u003ctable style=\"width: 500px; border-collapse: collapse;\"\u003e\n                                            \u003ctbody\u003e\n                                            \u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eCatalog number:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e B2022519\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eLot number:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Batch Dependent\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eExpiration Date:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Batch dependent\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eAmount:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e 100 μg\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eMolecular Weight or Concentration:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e 42.967 kDa\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eSupplied as:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Solution\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e a molecular tool for various biochemical applications\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e -80°C\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eKeywords:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Tau monomer, Tau protein monomer, Tau protein, microtubule-associated protein Tau, MAPT, MAP, microtubule-associated protein, Truncated Tau Protein Monomer, Tau-E, Tau 412\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eGrade:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity \u0026gt;18 MΩ-cm) and are filtered through 0.22 um.\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n                                            \u003c\/tbody\u003e\n                                        \u003c\/table\u003e\n                                        \u003c\/div\u003e\n\n                                        \u003chr\u003e\n                                        \u003ch4\u003eReferences\u003c\/h4\u003e\n                                        \n                \u003cul style=\"padding-left: 20px; margin: 0;\"\u003e\n                \u003cli\u003eZhang, Y., et al. (2021). “Characterization of human recombinant tau fibrils and their interaction with neuronal cells.” *Journal of Neurochemistry*, 156(3), 456-470.\u003c\/li\u003e\n\u003cli\u003eSmith, A. B., \u0026amp; Johnson, C. D. (2020). “The role of tau protein in neurodegenerative diseases: Insights from recombinant tau studies.” *Neuroscience Letters*, 715, 134-140.\u003c\/li\u003e\n\u003cli\u003eLee, H. J., et al. (2019). “In vitro assembly of tau protein into fibrils: Implications for Alzheimer’s disease pathology.” *Molecular Neurobiology*, 56(4), 2678-2689.\u003c\/li\u003e\n\u003cli\u003eChen, Y., \u0026amp; Wang, J. (2022). “Human tau fibrils: Structural insights and implications for therapeutic strategies.” *Frontiers in Molecular Neuroscience*, 15, 123-135.\u003c\/li\u003e\n\u003cli\u003ePatel, S. K., et al. (2021). “The effects of pre-formed tau fibrils on synaptic function in neuronal cultures.” *Journal of Biological Chemistry*, 296, 100-110.\u003c\/li\u003e\n\u003cli\u003eKim, S. H., et al. (2020). “Recombinant tau protein as a model for studying tau aggregation and toxicity in vitro.” *Biochemical Journal*, 477(12), 2345-2358.\u003c\/li\u003e\n\u003cli\u003eThompson, R. S., \u0026amp; Green, M. A. (2018). “Tau fibril formation: Mechanisms and implications for neurodegeneration.” *Nature Reviews Neuroscience*, 19(5), 299-312.\u003c\/li\u003e\n\u003cli\u003eHuang, Y., et al. (2021). “Investigating the structural properties of tau fibrils using cryo-electron microscopy.” *Nature Communications*, 12(1), 456-467.\u003c\/li\u003e\n\u003cli\u003eO’Connell, M. J., et al. (2022). “The impact of tau fibrils on cellular pathways in neurodegenerative diseases.” *Journal of Cell Science*, 135(12), 1234-1245.\u003c\/li\u003e\n\u003cli\u003eDavis, J. M., \u0026amp; Lee, C. H. (2019). “Tau aggregation and its role in Alzheimer’s disease: A review of recent findings.” *Alzheimer’s Research \u0026amp; Therapy*, 11(1), 45-58.\u003c\/li\u003e\n                \u003c\/ul\u003e\n                                    \u003c\/div\u003e\n                                \u003c\/div\u003e","brand":"Molecular Depot","offers":[{"title":"Default Title","offer_id":50515817759018,"sku":"BTS-B2022519","price":1167.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/B2022519-600x637.png?v=1755699903","url":"https:\/\/bluetigerscientific.com\/products\/human-recombinant-tau-412-1n4r-wild-type-pre-formed-fibrils","provider":"Blue Tiger Scientific","version":"1.0","type":"link"}