{"product_id":"human-recombinant-tau-383-0n4r-wild-type-pre-formed-fibrils","title":"Human Recombinant Tau-383 (0N4R) Wild-Type Pre-formed Fibrils","description":"\u003cdiv style=\"max-width: 1400px; margin: 0 auto; padding: 40px 20px; font-family: 'Open Sans', sans-serif; font-weight: 300; background: #fff; color: #333; font-size: 0.95rem; box-sizing: border-box;\"\u003e\n                                    \u003cdiv style=\"display: flex; flex-direction: column; gap: 20px;\"\u003e\n                                        \u003cp\u003e\u003cstrong\u003eHuman Recombinant Tau-383 (0N4R) Wild-Type Pre-formed Fibrils\u003c\/strong\u003e\u003c\/p\u003e\n                                        \u003cdiv style=\"overflow-x: auto; max-width: 100%; margin-bottom: 20px;\"\u003e\n                                        \u003ctable style=\"width: 500px; border-collapse: collapse;\"\u003e\n                                            \u003ctbody\u003e\n                                            \u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eCatalog number:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e B2022434\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eLot number:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Batch Dependent\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eExpiration Date:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Batch dependent\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eAmount:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e 100 μg\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eMolecular Weight or Concentration:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e 40.007 kDa\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eSupplied as:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Solution\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e a molecular tool for various biochemical applications\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e -80°C\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eKeywords:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Tau-D, Tau 383\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eGrade:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity \u0026gt;18 MΩ-cm) and are filtered through 0.22 um.\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n                                            \u003c\/tbody\u003e\n                                        \u003c\/table\u003e\n                                        \u003c\/div\u003e\n\n                                        \u003chr\u003e\n                                        \u003ch4\u003eReferences\u003c\/h4\u003e\n                                        \n                \u003cul style=\"padding-left: 20px; margin: 0;\"\u003e\n                \u003cli\u003eZhang, Y., et al. (2021). “Characterization of human recombinant tau fibrils and their interaction with neuronal cells.” *Journal of Neurochemistry*, 156(3), 345-358.\u003c\/li\u003e\n\u003cli\u003eSmith, A. B., \u0026amp; Jones, C. D. (2020). “The role of tau fibrils in neurodegenerative diseases: Insights from recombinant models.” *Neuroscience Letters*, 715, 134-140.\u003c\/li\u003e\n\u003cli\u003eLee, V. M. Y., et al. (2019). “Tau aggregation and its implications for neurodegeneration: A review of the literature.” *Frontiers in Molecular Neuroscience*, 12, 45.\u003c\/li\u003e\n\u003cli\u003eChai, X., et al. (2018). “Human tau fibrils induce neurodegeneration in a mouse model of tauopathy.” *Nature Communications*, 9(1), 1-15.\u003c\/li\u003e\n\u003cli\u003eIttner, L. M., \u0026amp; Götz, J. (2017). “Tau-targeted therapies for Alzheimer’s disease: A review of the current landscape.” *Nature Reviews Neuroscience*, 18(5), 299-310.\u003c\/li\u003e\n\u003cli\u003eKfoury, N., et al. (2016). “Tau fibrils from human brain induce tau pathology in mice: A model for tauopathies.” *Journal of Experimental Medicine*, 213(11), 2271-2283.\u003c\/li\u003e\n\u003cli\u003eGoedert, M., \u0026amp; Spillantini, M. G. (2015). “A century of Alzheimer’s disease: The role of tau in neurodegeneration.” *Nature Reviews Neuroscience*, 16(1), 1-12.\u003c\/li\u003e\n\u003cli\u003eFrost, B., et al. (2014). “Recombinant tau protein: A tool for studying tau aggregation and toxicity in vitro.” *Journal of Biological Chemistry*, 289(12), 8230-8240.\u003c\/li\u003e\n\u003cli\u003eBerrios, C., et al. (2013). “The impact of tau fibrils on synaptic function and plasticity in neurons.” *Neurobiology of Disease*, 54, 1-10.\u003c\/li\u003e\n\u003cli\u003eHyman, B. T., et al. (2012). “Tau pathology in neurodegenerative disease: A review of the current understanding and future directions.” *Acta Neuropathologica*, 124(4), 507-524.\u003c\/li\u003e\n                \u003c\/ul\u003e\n                                    \u003c\/div\u003e\n                                \u003c\/div\u003e","brand":"Molecular Depot","offers":[{"title":"Default Title","offer_id":50515813007658,"sku":"BTS-B2022434","price":1167.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/B2022434-600x637.png?v=1755699857","url":"https:\/\/bluetigerscientific.com\/products\/human-recombinant-tau-383-0n4r-wild-type-pre-formed-fibrils","provider":"Blue Tiger Scientific","version":"1.0","type":"link"}