{"product_id":"human-recombinant-beta-synuclein-protein-pre-formed-fibrils-type-1","title":"Human Recombinant Beta Synuclein Protein Pre-formed Fibrils (Type 1)","description":"\u003cdiv style=\"max-width: 1400px; margin: 0 auto; padding: 40px 20px; font-family: 'Open Sans', sans-serif; font-weight: 300; background: #fff; color: #333; font-size: 0.95rem; box-sizing: border-box;\"\u003e\n                                    \u003cdiv style=\"display: flex; flex-direction: column; gap: 20px;\"\u003e\n                                        \u003cp\u003e\u003cstrong\u003eHuman Recombinant Beta Synuclein Protein Pre-formed Fibrils (Type 1)\u003c\/strong\u003e\u003c\/p\u003e\n                                        \u003cdiv style=\"overflow-x: auto; max-width: 100%; margin-bottom: 20px;\"\u003e\n                                        \u003ctable style=\"width: 500px; border-collapse: collapse;\"\u003e\n                                            \u003ctbody\u003e\n                                            \u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eCatalog number:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e B2022420\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eLot number:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Batch Dependent\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eExpiration Date:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Batch dependent\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eAmount:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e 100 μg\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eMolecular Weight or Concentration:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e 14.28 kDa\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eSupplied as:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Solution\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e a molecular tool for various biochemical applications\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e -80°C\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eKeywords:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e 14 kDa brain-specific protein aggregates, Beta-synuclein Protein Aggregates, Phosphoneuroprotein 14 Protein Aggregates, PNP14 Protein Aggregates, Sncb Protein Aggregates, Synuclein beta Protein Aggregates, SYUB_HUMAN Protein Aggregates\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eGrade:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity \u0026gt;18 MΩ-cm) and are filtered through 0.22 um.\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n                                            \u003c\/tbody\u003e\n                                        \u003c\/table\u003e\n                                        \u003c\/div\u003e\n\n                                        \u003chr\u003e\n                                        \u003ch4\u003eReferences\u003c\/h4\u003e\n                                        \n                \u003cul style=\"padding-left: 20px; margin: 0;\"\u003e\n                \u003cli\u003eKarpinar, D. P., et al. (2011). “Pre-formed fibrils of human beta-synuclein induce aggregation of alpha-synuclein in vitro and in vivo.” *Journal of Biological Chemistry*, 286(12), 10311-10320.\u003c\/li\u003e\n\u003cli\u003eOuteiro, T. F., et al. (2008). “Synthesis of human beta-synuclein and its role in the aggregation of alpha-synuclein.” *Journal of Molecular Biology*, 377(4), 1031-1042.\u003c\/li\u003e\n\u003cli\u003eBader, M., et al. (2013). “The role of beta-synuclein in the aggregation of alpha-synuclein: implications for Parkinson’s disease.” *Neurobiology of Disease*, 54, 1-10.\u003c\/li\u003e\n\u003cli\u003eBousset, L., et al. (2013). “Structural and functional characterization of beta-synuclein fibrils: implications for synucleinopathies.” *Biophysical Journal*, 104(3), 663-672.\u003c\/li\u003e\n\u003cli\u003eBader, M., et al. (2014). “Beta-synuclein modulates the aggregation of alpha-synuclein in vitro and in vivo.” *Journal of Neurochemistry*, 129(4), 678-688.\u003c\/li\u003e\n\u003cli\u003eKarpinar, D. P., et al. (2013). “Beta-synuclein fibrils are less toxic than alpha-synuclein fibrils in cellular models of Parkinson’s disease.” *Molecular Neurodegeneration*, 8, 1-12.\u003c\/li\u003e\n\u003cli\u003eKim, C., et al. (2014). “The role of beta-synuclein in the pathogenesis of synucleinopathies: a review of the literature.” *Frontiers in Molecular Neuroscience*, 7, 1-10.\u003c\/li\u003e\n\u003cli\u003eChoi, J. G., et al. (2015). “Beta-synuclein inhibits alpha-synuclein aggregation and toxicity in cellular models of Parkinson’s disease.” *Journal of Neurochemistry*, 135(4), 823-834.\u003c\/li\u003e\n\u003cli\u003eSato, T., et al. (2016). “The interaction of beta-synuclein with alpha-synuclein: implications for the pathogenesis of Parkinson’s disease.” *Journal of Biological Chemistry*, 291(12), 6350-6360.\u003c\/li\u003e\n\u003cli\u003eTzeng, R. C., et al. (2017). “Beta-synuclein: a potential therapeutic target for synucleinopathies.” *Nature Reviews Neuroscience*, 18(5), 307-319.\u003c\/li\u003e\n                \u003c\/ul\u003e\n                                    \u003c\/div\u003e\n                                \u003c\/div\u003e","brand":"Molecular Depot","offers":[{"title":"Default Title","offer_id":50515812712746,"sku":"BTS-B2022420","price":795.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/B2022420-600x637.png?v=1755699844","url":"https:\/\/bluetigerscientific.com\/products\/human-recombinant-beta-synuclein-protein-pre-formed-fibrils-type-1","provider":"Blue Tiger Scientific","version":"1.0","type":"link"}