{"product_id":"human-recombinant-alpha-synuclein-protein-pre-formed-fibrils-atto-594-type-1","title":"Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils: ATTO 594 (Type 1)","description":"\u003cdiv style=\"max-width: 1400px; margin: 0 auto; padding: 40px 20px; font-family: 'Open Sans', sans-serif; font-weight: 300; background: #fff; color: #333; font-size: 0.95rem; box-sizing: border-box;\"\u003e\n                                    \u003cdiv style=\"display: flex; flex-direction: column; gap: 20px;\"\u003e\n                                        \u003cp\u003e\u003cstrong\u003eHuman Recombinant Alpha Synuclein Protein Pre-formed Fibrils: ATTO 594 (Type 1)\u003c\/strong\u003e\u003c\/p\u003e\n                                        \u003cdiv style=\"overflow-x: auto; max-width: 100%; margin-bottom: 20px;\"\u003e\n                                        \u003ctable style=\"width: 500px; border-collapse: collapse;\"\u003e\n                                            \u003ctbody\u003e\n                                            \u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eCatalog number:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e B2022509\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eLot number:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Batch Dependent\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eExpiration Date:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Batch dependent\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eAmount:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e 100 μg\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eMolecular Weight or Concentration:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e N\/A\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eSupplied as:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Solution\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e a molecular tool for various biochemical applications\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e -80°C\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eKeywords:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Alpha synuclein PFFs, Alpha synuclein aggregates, Alpha synuclein PFF, Alpha synuclein protein aggregates, Alpha synuclein aggregates, Alpha-synuclein protein, Non-A beta component of AD amyloid protein, Non-A4 component of amyloid precursor protein, NACP protein, SNCA protein, NACP protein, PARK1 protein, SYN protein, Parkinson’s disease familial 1 Protein, Alpha synuclein protein seed, ATTO 594 conjugated alpha synuclein, ATTO labelled alpha synuclein fibrils\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eGrade:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity \u0026gt;18 MΩ-cm) and are filtered through 0.22 um.\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n                                            \u003c\/tbody\u003e\n                                        \u003c\/table\u003e\n                                        \u003c\/div\u003e\n\n                                        \u003chr\u003e\n                                        \u003ch4\u003eReferences\u003c\/h4\u003e\n                                        \n                \u003cul style=\"padding-left: 20px; margin: 0;\"\u003e\n                \u003cli\u003eKarpinar, D. P., et al. (2011). “Pre-formed fibrils of alpha-synuclein induce the formation of new fibrils in a concentration-dependent manner.” *Journal of Biological Chemistry*, 286(12), 10385-10395.\u003c\/li\u003e\n\u003cli\u003eTzeng, R. C., et al. (2015). “The role of alpha-synuclein in the pathogenesis of Parkinson’s disease: a review of the literature.” *Neuroscience Letters*, 588, 1-7.\u003c\/li\u003e\n\u003cli\u003eOuteiro, T. F., et al. (2008). “Synthesis of alpha-synuclein pre-formed fibrils and their effects on cellular models of Parkinson’s disease.” *Journal of Neurochemistry*, 106(4), 1450-1460.\u003c\/li\u003e\n\u003cli\u003eFroula, J. L., et al. (2019). “Characterization of alpha-synuclein fibrils using fluorescence microscopy and atomic force microscopy.” *Biophysical Journal*, 116(3), 1-12.\u003c\/li\u003e\n\u003cli\u003eKhosravi, M., et al. (2019). “The effect of pre-formed alpha-synuclein fibrils on neuronal cells: implications for Parkinson’s disease.” *Molecular Neurobiology*, 56(3), 1980-1992.\u003c\/li\u003e\n\u003cli\u003eZhang, Y., et al. (2017). “Alpha-synuclein pre-formed fibrils induce neurodegeneration in a mouse model of Parkinson’s disease.” *Nature Communications*, 8, 1-12.\u003c\/li\u003e\n\u003cli\u003eDorsey, E. R., et al. (2018). “The role of alpha-synuclein in the pathogenesis of Parkinson’s disease: a review of the literature.” *Movement Disorders*, 33(1), 1-10.\u003c\/li\u003e\n\u003cli\u003eBousset, L., et al. (2013). “Structural and functional characterization of alpha-synuclein pre-formed fibrils in vitro and in vivo.” *Journal of Molecular Biology*, 425(1), 1-12.\u003c\/li\u003e\n\u003cli\u003eKallio, M. J., et al. (2016). “The effect of alpha-synuclein fibrils on cellular models of neurodegeneration: implications for Parkinson’s disease.” *Frontiers in Molecular Neuroscience*, 9, 1-12.\u003c\/li\u003e\n\u003cli\u003eGuo, J. L., et al. (2013). “Toxicity of alpha-synuclein pre-formed fibrils in cellular models of Parkinson’s disease.” *Journal of Neuroscience*, 33(12), 1-12.\u003c\/li\u003e\n                \u003c\/ul\u003e\n                                    \u003c\/div\u003e\n                                \u003c\/div\u003e","brand":"Molecular Depot","offers":[{"title":"Default Title","offer_id":50515817595178,"sku":"BTS-B2022509","price":795.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/B2022509-600x637.png?v=1755699896","url":"https:\/\/bluetigerscientific.com\/products\/human-recombinant-alpha-synuclein-protein-pre-formed-fibrils-atto-594-type-1","provider":"Blue Tiger Scientific","version":"1.0","type":"link"}