{"product_id":"concanavalin-a-magnetic-beads-1-um-1","title":"Concanavalin A Magnetic Beads (1 μm)","description":"\u003cdiv style=\"max-width:1400px; margin:0 auto; padding:40px 20px; font-family:'Open Sans',sans-serif; font-weight:300; background:#fff; color:#333; font-size:0.95rem; box-sizing:border-box;\"\u003e\n  \u003cdiv style=\"display:flex; flex-direction:column; gap:20px;\"\u003e\n\u003ch2 style=\"margin:0; font-weight:600;\"\u003eConcanavalin A Magnetic Beads (1 μm) – Catalog #B2025473\u003c\/h2\u003e\n\u003cp\u003eConcanavalin A (Con A) magnetic beads (Catalog #B2025473) are small, 1 µm magnetic particles coated with concanavalin A lectin, supplied as 1 mL in solution. Concanavalin A is a plant lectin from the jack bean that binds specifically to α-D-mannose and α-D-glucose residues on glycoproteins and glycolipids. The immobilization of Con A on magnetic beads combines the specificity and binding capacity of the lectin with the convenience of magnetic separation, allowing researchers to isolate and purify glycoproteins from complex samples without centrifugation.\u003c\/p\u003e\n\u003cdiv style=\"overflow-x:auto; max-width:100%; margin-bottom:20px;\"\u003e\n\u003ctable style=\"width:100%; max-width:640px; border-collapse:collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eCatalog number:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eB2025473\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eLot number:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eBatch dependent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eExpiration Date:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eBatch dependent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eAmount:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003e1 mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eBead size:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003e1 µm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eBead composition:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eMagnetic particles coated with concanavalin A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eLectin binding specificity:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eα-D-mannose and α-D-glucose\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eSupplied as:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eSolution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eGlycoprotein isolation and purification, affinity separation, magnetic bead-based bioassays, cell surface glycoprotein detection\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003e2–8°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eKeywords:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eConcanavalin A beads, concanavalin A magnetic particles, Con A magnetic beads, lectin affinity beads, mannose binding beads, glycoprotein isolation beads, magnetic affinity beads, concanavalin A coated beads\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eGrade:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eBiotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity \u0026gt;18 MΩ-cm) and are filtered through 0.22 µm.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eScientific Overview\u003c\/h3\u003e\n\u003cp\u003eConcanavalin A is a tetrameric plant lectin (approximately 104 kDa) derived from the jack bean that has been extensively characterized both structurally and biochemically. It recognizes and binds specifically to α-linked mannose and glucose residues on glycoproteins, glycolipids, and polysaccharides. This specificity makes Con A an invaluable tool for the selective isolation and purification of glycoproteins from cell lysates, serum, and other biological samples. By immobilizing Con A onto magnetic particles, researchers can perform rapid, hands-on affinity separation without relying on centrifugation. The 1 µm bead size offers a large surface area and efficient magnetic responsiveness.\u003c\/p\u003e\n\u003cp\u003eKey applications include:\u003c\/p\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003eIsolation and purification of glycoproteins from cell lysates and serum\u003c\/li\u003e\n\u003cli\u003eEnrichment of mannose- and glucose-containing proteins for proteomic analysis\u003c\/li\u003e\n\u003cli\u003eDetection and quantification of glycosylated targets in bioassays\u003c\/li\u003e\n\u003cli\u003eGlycoprotein depletion or removal from samples\u003c\/li\u003e\n\u003cli\u003eCell surface protein isolation and characterization\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eUsage \u0026amp; Handling Guidance\u003c\/h3\u003e\n\u003cp\u003eStore the suspension at 2–8°C. Gently mix before use and resuspend if beads have settled. Optimize the bead volume, incubation time, and washing steps for your specific glycoprotein target.\u003c\/p\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eBinding:\u003c\/strong\u003e Incubate beads with your sample (cell lysate, serum, or purified protein) to allow Con A lectin domains to capture glycoproteins; typical incubation times range from 30 minutes to several hours at 4°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSeparation:\u003c\/strong\u003e Apply a magnetic field to collect beads and bound glycoproteins; remove the supernatant.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWashing:\u003c\/strong\u003e Resuspend and wash beads multiple times with appropriate buffer to remove non-specific binding.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElution:\u003c\/strong\u003e Bound glycoproteins can be eluted by competitive displacement with free mannose or methyl α-D-mannopyranoside, or by changing pH or ionic strength.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eWhat You Get\u003c\/h3\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003e1 mL of concanavalin A magnetic bead suspension\u003c\/li\u003e\n\u003cli\u003e1 µm magnetic particles coated with active lectin\u003c\/li\u003e\n\u003cli\u003eReady-to-use formulation for rapid glycoprotein isolation\u003c\/li\u003e\n\u003cli\u003eFor research use only (RUO)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eWhy Researchers Choose It\u003c\/h3\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003eHigh specificity for mannose and glucose residues on glycoproteins\u003c\/li\u003e\n\u003cli\u003eMagnetic separation allows fast, hands-on isolation without centrifugation\u003c\/li\u003e\n\u003cli\u003eSmall bead size (1 µm) for efficient binding and quick magnetic response\u003c\/li\u003e\n\u003cli\u003eSimple, scalable workflow for rapid sample preparation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eFrequently Asked Questions (FAQ)\u003c\/h3\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhat does concanavalin A bind?\u003c\/strong\u003e\u003cbr\u003eCon A specifically recognizes α-linked mannose and glucose residues on glycoproteins, glycolipids, and polysaccharides. It does not bind N-linked oligosaccharides containing sialic acid or galactose in terminal positions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow do I elute bound glycoproteins?\u003c\/strong\u003e\u003cbr\u003eGlycoproteins can be eluted by adding competitive substrates such as methyl α-D-mannopyranoside (5–100 mM) or free mannose, or by changing pH or salt concentration. Request the COA or contact us for lot-specific elution protocols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCan I use these beads in automated systems?\u003c\/strong\u003e\u003cbr\u003eYes, the small size and strong magnetic response make them compatible with magnetic bead handling robots and automated liquid handlers.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow should I store them?\u003c\/strong\u003e\u003cbr\u003eStore at 2–8°C. Gently mix before use to ensure uniform suspension.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCan I get a COA or TDS?\u003c\/strong\u003e\u003cbr\u003eYes. Request a quote or contact us and we will provide available lot documentation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"margin-top:20px; font-weight:bold; color:#c8102e;\"\u003eThis product is for Research Use Only (RUO). It is not intended for diagnostic or therapeutic use in humans or animals.\u003c\/div\u003e\n\u003chr\u003e\n\u003ch4\u003eReferences\u003c\/h4\u003e\n\u003cul style=\"padding-left:0; margin:0; list-style:none;\"\u003e\n\u003cli style=\"display:flex; justify-content:space-between; align-items:flex-start; gap:12px; padding:8px 0; border-bottom:1px solid #eee;\"\u003e\n\u003cspan style=\"flex:1;\"\u003eLee YC, Block G, Chen H, Folch-Puy E, Foronjy R, Jalili R, Jendresen CB, Kimura M, Kraft E, Lindemose S, Lu J, McLain T, Nutt L, Ramon-Garcia S, Smith J, Spivak A, Wang ML, Zanic M, Lin SH. One-step isolation of plasma membrane proteins using magnetic beads with immobilized concanavalin A. \u003cem\u003eProtein Expr Purif.\u003c\/em\u003e 2008;62(2):223-9.\u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/j.pep.2008.08.003\" target=\"_blank\" rel=\"noopener\" style=\"flex-shrink:0; margin-top:2px;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height:28px; width:auto;\"\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli style=\"display:flex; justify-content:space-between; align-items:flex-start; gap:12px; padding:8px 0; border-bottom:1px solid #eee;\"\u003e\n\u003cspan style=\"flex:1;\"\u003eLee YC, Srajer Gajdosik M, Josic D, Lin SH. Plasma membrane isolation using immobilized concanavalin A magnetic beads. \u003cem\u003eMethods Mol Biol.\u003c\/em\u003e 2012;909:29-41.\u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1007\/978-1-61779-959-4_3\" target=\"_blank\" rel=\"noopener\" style=\"flex-shrink:0; margin-top:2px;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height:28px; width:auto;\"\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli style=\"display:flex; justify-content:space-between; align-items:flex-start; gap:12px; padding:8px 0; border-bottom:1px solid #eee;\"\u003e\n\u003cspan style=\"flex:1;\"\u003eLee YC, Liu HC, Chuang C, Lin SH. Lectin-Magnetic Beads for Plasma Membrane Isolation. \u003cem\u003eCold Spring Harb Protoc.\u003c\/em\u003e 2015;2015(7):674-8.\u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1101\/pdb.prot074427\" target=\"_blank\" rel=\"noopener\" style=\"flex-shrink:0; margin-top:2px;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height:28px; width:auto;\"\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli style=\"display:flex; justify-content:space-between; align-items:flex-start; gap:12px; padding:8px 0; border-bottom:1px solid #eee;\"\u003e\n\u003cspan style=\"flex:1;\"\u003eKo SM, Cho SY, Oh MJ, Kwon J, Vaidya B, Kim D. Application of Concanavalin A-Linked Magnetic Beads for the Detection of Hepatitis A Virus. \u003cem\u003eJ Food Prot.\u003c\/em\u003e 2018;81(12):1997-2002.\u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.4315\/0362-028X.JFP-18-218\" target=\"_blank\" rel=\"noopener\" style=\"flex-shrink:0; margin-top:2px;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height:28px; width:auto;\"\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e","brand":"Molecular Depot","offers":[{"title":"Default Title","offer_id":52813631914282,"sku":"BTS-B2025473","price":1205.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/B2025473_41397cad-7ae3-471e-946a-bf3adfb547dc.png?v=1790899992","url":"https:\/\/bluetigerscientific.com\/products\/concanavalin-a-magnetic-beads-1-um-1","provider":"Blue Tiger Scientific","version":"1.0","type":"link"}