{"product_id":"concanavalin-a-lectin-con-a-texas-red","title":"Concanavalin A Lectin (Con A) – Texas Red","description":"\u003cdiv style=\"max-width:1400px; margin:0 auto; padding:40px 20px; font-family:'Open Sans',sans-serif; font-weight:300; background:#fff; color:#333; font-size:0.95rem; box-sizing:border-box;\"\u003e\n  \u003cdiv style=\"display:flex; flex-direction:column; gap:20px;\"\u003e\n\u003ch2 style=\"margin:0; font-weight:600;\"\u003eConcanavalin A Lectin (Con A) – Texas Red – Catalog #B2025513\u003c\/h2\u003e\n\u003cp\u003eConcanavalin A – Texas Red (Catalog #B2025513) combines the carbohydrate specificity of Concanavalin A, the legume lectin from jack bean (\u003cem\u003eCanavalia ensiformis\u003c\/em\u003e), with the red fluorescence of Texas Red. Supplied as 2 mg in liquid form, it is used to label and visualize mannose- and glucose-containing glycoproteins and glycolipids on cells and tissue sections.\u003c\/p\u003e\n\u003cdiv style=\"overflow-x:auto; max-width:100%; margin-bottom:20px;\"\u003e\n\u003ctable style=\"width:100%; max-width:640px; border-collapse:collapse;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eCatalog number:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eB2025513\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eLot number:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eBatch dependent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eExpiration Date:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eBatch dependent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eAmount:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003e2 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eMolecular Weight or Concentration:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eN\/A\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eSupplied as:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eLiquid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eJack bean (\u003cem\u003eCanavalia ensiformis\u003c\/em\u003e)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eLabel:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eTexas Red (Ex ~589 nm \/ Em ~615 nm)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eCarbohydrate specificity:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eα-D-mannosyl and α-D-glucosyl residues\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eFluorescence microscopy, flow cytometry, cell-surface glycoconjugate labeling, dual-color labeling with green fluorophores\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003e2–8°C, protected from light\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eKeywords:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eConcanavalin A, Con A, ConA Texas Red, Texas Red Concanavalin A, Texas Red lectin, fluorescent Con A, Canavalia ensiformis lectin, jack bean lectin, mannose-binding lectin\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n\u003ctd style=\"width:150px; padding:6px 10px 6px 0; vertical-align:top;\"\u003e\u003cstrong\u003eGrade:\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:6px 0;\"\u003eBiotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity \u0026gt;18 MΩ-cm) and are filtered through 0.22 um.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eScientific Overview\u003c\/h3\u003e\n\u003cp\u003eConcanavalin A is one of the most thoroughly characterized lectins. It recognizes terminal and internal α-D-mannosyl and α-D-glucosyl residues and binds the trimannoside core common to N-linked glycans with high affinity; crystal structures of Con A–trimannoside complexes show how all three sugar residues are held in an extended binding cleft. Carbohydrate binding depends on bound manganese and calcium ions.\u003c\/p\u003e\n\u003cp\u003eTexas Red (sulforhodamine 101 derivative) was introduced as a hydrophilic, red-emitting fluorophore designed to be used alongside fluorescein in dual-parameter flow cytometry and fluorescence microscopy. Its emission near 615 nm is well separated from green fluorophores, so Con A – Texas Red can be combined with FITC- or GFP-labeled probes.\u003c\/p\u003e\n\u003cp\u003eKey applications include:\u003c\/p\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003eFluorescent staining of cell-surface glycoproteins and glycolipids\u003c\/li\u003e\n\u003cli\u003eFlow cytometric analysis of glycoconjugate expression\u003c\/li\u003e\n\u003cli\u003eVisualizing glycoprotein distribution in cells and tissue sections\u003c\/li\u003e\n\u003cli\u003eDual-color labeling with green-emitting probes\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eUsage \u0026amp; Handling Guidance\u003c\/h3\u003e\n\u003cp\u003eStore at 2–8°C and protect from light. Titrate the conjugate for each cell type or tissue to find the concentration that gives the best signal-to-background ratio.\u003c\/p\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eBuffers:\u003c\/strong\u003e Avoid EDTA, EGTA, and other chelators, which strip the metal ions Con A needs for sugar binding.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecificity control:\u003c\/strong\u003e Pre-incubate the lectin with a competing sugar such as methyl α-D-mannopyranoside; loss of staining confirms carbohydrate-specific binding.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImaging:\u003c\/strong\u003e Use filter sets suited to Texas Red (excitation ~590 nm, emission ~615 nm).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eWhat You Get\u003c\/h3\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003e2 mg of Concanavalin A conjugated to Texas Red, supplied as liquid\u003c\/li\u003e\n\u003cli\u003eA well-characterized mannose\/glucose-specific lectin probe\u003c\/li\u003e\n\u003cli\u003eRed fluorescence suited to multicolor experiments\u003c\/li\u003e\n\u003cli\u003eFor research use only (RUO)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eWhy Researchers Choose It\u003c\/h3\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003eExtensively characterized carbohydrate specificity backed by crystal structures\u003c\/li\u003e\n\u003cli\u003eBright red emission that separates cleanly from green channels\u003c\/li\u003e\n\u003cli\u003eWorks in both imaging and flow cytometry workflows\u003c\/li\u003e\n\u003cli\u003eSimple competition control with methyl α-D-mannopyranoside\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 style=\"margin-top:30px;\"\u003eFrequently Asked Questions (FAQ)\u003c\/h3\u003e\n\u003cul style=\"padding-left:20px;\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhat does Concanavalin A bind?\u003c\/strong\u003e\u003cbr\u003eα-D-mannosyl and α-D-glucosyl residues, including the trimannoside core found in N-linked glycans.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhat are the excitation and emission maxima of Texas Red?\u003c\/strong\u003e\u003cbr\u003eApproximately 589 nm excitation and 615 nm emission.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCan I combine it with FITC or GFP?\u003c\/strong\u003e\u003cbr\u003eYes. Texas Red was developed for use alongside fluorescein, and its emission is well separated from green fluorophores.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhy is my staining weak?\u003c\/strong\u003e\u003cbr\u003eCheck that your buffers contain no chelators such as EDTA, since Con A requires bound metal ions to bind sugars, and titrate the conjugate concentration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHow do I confirm the staining is specific?\u003c\/strong\u003e\u003cbr\u003eRun a control with a competing sugar such as methyl α-D-mannopyranoside; specific staining should be strongly reduced.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"margin-top:20px; font-weight:bold; color:#c8102e;\"\u003eThis product is for Research Use Only (RUO). It is not intended for diagnostic or therapeutic use in humans or animals.\u003c\/div\u003e\n\u003chr\u003e\n\u003ch4\u003eReferences\u003c\/h4\u003e\n\u003cul style=\"padding-left:0; margin:0; list-style:none;\"\u003e\n\u003cli style=\"display:flex; justify-content:space-between; align-items:flex-start; gap:12px; padding:8px 0; border-bottom:1px solid #eee;\"\u003e\n\u003cspan style=\"flex:1;\"\u003eNaismith JH, Field RA. Structural basis of trimannoside recognition by concanavalin A. \u003cem\u003eJ Biol Chem.\u003c\/em\u003e 1996;271(2):972-976.\u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1074\/jbc.271.2.972\" target=\"_blank\" rel=\"noopener\" style=\"flex-shrink:0; margin-top:2px;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height:28px; width:auto;\"\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli style=\"display:flex; justify-content:space-between; align-items:flex-start; gap:12px; padding:8px 0; border-bottom:1px solid #eee;\"\u003e\n\u003cspan style=\"flex:1;\"\u003eLoris R, Maes D, Poortmans F, Wyns L, Bouckaert J. A structure of the complex between concanavalin A and methyl-3,6-di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside reveals two binding modes. \u003cem\u003eJ Biol Chem.\u003c\/em\u003e 1996;271(48):30614-30618.\u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8940035\/\" target=\"_blank\" rel=\"noopener\" style=\"flex-shrink:0; margin-top:2px;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height:28px; width:auto;\"\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli style=\"display:flex; justify-content:space-between; align-items:flex-start; gap:12px; padding:8px 0; border-bottom:1px solid #eee;\"\u003e\n\u003cspan style=\"flex:1;\"\u003eTitus JA, Haugland R, Sharrow SO, Segal DM. Texas Red, a hydrophilic, red-emitting fluorophore for use with fluorescein in dual parameter flow microfluorometric and fluorescence microscopic studies. \u003cem\u003eJ Immunol Methods.\u003c\/em\u003e 1982;50(2):193-204.\u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1016\/0022-1759(82)90225-3\" target=\"_blank\" rel=\"noopener\" style=\"flex-shrink:0; margin-top:2px;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height:28px; width:auto;\"\u003e\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e","brand":"Molecular Depot","offers":[{"title":"Default Title","offer_id":52805452071210,"sku":"BTS-B2025513","price":1175.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/B2025513.png?v=1790798105","url":"https:\/\/bluetigerscientific.com\/products\/concanavalin-a-lectin-con-a-texas-red","provider":"Blue Tiger Scientific","version":"1.0","type":"link"}