{"product_id":"amine-modified-polystyrene-latex-beads-5-0-5-9-um-5-w-v-research-use-only-non-medical","title":"Amine-Modified Polystyrene Latex Beads (5.0-5.9 um, 5% w\/v) – Research Use Only – Non Medical","description":"\u003cdiv style=\"max-width:1400px; margin:0 auto; padding:40px 20px; font-family:'Open Sans',sans-serif; font-weight:300; background:#fff; color:#333; font-size:0.95rem; box-sizing:border-box;\"\u003e\n  \u003cdiv style=\"display:flex; flex-direction:column; gap:20px;\"\u003e\n    \u003ch2 style=\"margin:0; font-weight:600;\"\u003eAmine-Modified Polystyrene Latex Beads (5.0-5.9 µm, 5% w\/v) – Catalog #B2025677\u003c\/h2\u003e\n    \u003cp\u003e\n      Amine-Modified Polystyrene Latex Beads (5.0-5.9 µm, 5% w\/v) (Catalog #B2025677) are uniform, surface-functionalized 5 µm polystyrene microspheres supplied as a 5 mL 5% aqueous suspension. \n      The primary amine groups on the surface enable easy covalent conjugation to carboxyl-containing molecules (proteins, antibodies, peptides, dyes, etc.) using standard EDC\/NHS chemistry. \n      These larger aminated beads are ideal for microscopy, flow cytometry, phagocytosis studies, immunoassays, cell labeling, and the development of custom microparticle-based diagnostic or therapeutic tools.\n    \u003c\/p\u003e\n    \n    \u003c!-- SPEC TABLE --\u003e\n    \u003cdiv style=\"overflow-x:auto; max-width:100%; margin-bottom:20px;\"\u003e\n      \u003ctable style=\"width:500px; border-collapse:collapse;\"\u003e\n        \u003ctbody\u003e\n          \u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n            \u003ctd style=\"width:150px; padding-right:10px;\"\u003e\u003cstrong\u003eCatalog number:\u003c\/strong\u003e\u003c\/td\u003e\n            \u003ctd\u003eB2025677\u003c\/td\u003e\n          \u003c\/tr\u003e\n          \u003ctr style=\"border-bottom:1px solid #ddd;\"\u003e\n            \u003ctd style=\"width:150px; padding-right:10px;\"\u003e\u003cstrong\u003eLot number:\u003c\/strong\u003e\u003c\/td\u003e\n            \u003ctd\u003eBatch Dependent\u003c\/td\u003e\n          \u003c\/tr\u003e\n          \u003ctr style=\"border-bottom:1px solid:#ddd;\"\u003e\n            \u003ctd style=\"width:150px; padding-right:10px;\"\u003e\u003cstrong\u003eExpiration Date:\u003c\/strong\u003e\u003c\/td\u003e\n            \u003ctd\u003eBatch dependent\u003c\/td\u003e\n          \u003c\/tr\u003e\n          \u003ctr style=\"border-bottom:1px solid:#ddd;\"\u003e\n            \u003ctd style=\"width:150px; padding-right:10px;\"\u003e\u003cstrong\u003eAmount:\u003c\/strong\u003e\u003c\/td\u003e\n            \u003ctd\u003e5 mL\u003c\/td\u003e\n          \u003c\/tr\u003e\n          \u003ctr style=\"border-bottom:1px solid:#ddd;\"\u003e\n            \u003ctd style=\"width:150px; padding-right:10px;\"\u003e\u003cstrong\u003eMolecular Weight or Concentration:\u003c\/strong\u003e\u003c\/td\u003e\n            \u003ctd\u003e5% (w\/v) suspension\u003c\/td\u003e\n          \u003c\/tr\u003e\n          \u003ctr style=\"border-bottom:1px solid:#ddd;\"\u003e\n            \u003ctd style=\"width:150px; padding-right:10px;\"\u003e\u003cstrong\u003eSupplied as:\u003c\/strong\u003e\u003c\/td\u003e\n            \u003ctd\u003eAqueous suspension\u003c\/td\u003e\n          \u003c\/tr\u003e\n          \u003ctr style=\"border-bottom:1px solid:#ddd;\"\u003e\n            \u003ctd style=\"width:150px; padding-right:10px;\"\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e\u003c\/td\u003e\n            \u003ctd\u003eCovalent bioconjugation, immunoassay development, targeted microparticle preparation, phagocytosis studies, cell labeling, agglutination assays, and surface functionalization\u003c\/td\u003e\n          \u003c\/tr\u003e\n          \u003ctr style=\"border-bottom:1px solid:#ddd;\"\u003e\n            \u003ctd style=\"width:150px; padding-right:10px;\"\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e\u003c\/td\u003e\n            \u003ctd\u003e2-8°C (do not freeze)\u003c\/td\u003e\n          \u003c\/tr\u003e\n          \u003ctr style=\"border-bottom:1px solid:#ddd;\"\u003e\n            \u003ctd style=\"width:150px; padding-right:10px;\"\u003e\u003cstrong\u003eKeywords:\u003c\/strong\u003e\u003c\/td\u003e\n            \u003ctd\u003eAmine-Modified Polystyrene Microspheres, Amine-Functionalized Polystyrene Latex Particles, Amine-Modified Polystyrene Beads, Amine-Functional Polystyrene Latex Beads, Amine-Modified Polystyrene Nanoparticles, Amine-Modified Polystyrene Colloids, Amine-Functionalized Polystyrene Spheres\u003c\/td\u003e\n          \u003c\/tr\u003e\n          \u003ctr style=\"border-bottom:1px solid:#ddd;\"\u003e\n            \u003ctd style=\"width:150px; padding-right:10px;\"\u003e\u003cstrong\u003eGrade:\u003c\/strong\u003e\u003c\/td\u003e\n            \u003ctd\u003eBiotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity \u0026gt;18 MΩ-cm) and are filtered through 0.22 um.\u003c\/td\u003e\n          \u003c\/tr\u003e\n        \u003c\/tbody\u003e\n      \u003c\/table\u003e\n    \u003c\/div\u003e\n    \n    \u003c!-- SCIENTIFIC OVERVIEW --\u003e\n    \u003ch3 style=\"margin-top:30px;\"\u003eScientific Overview\u003c\/h3\u003e\n    \u003cp\u003e\n      These 5.0–5.9 µm amine-modified polystyrene latex beads feature reactive primary amine groups on the surface, allowing straightforward covalent attachment of carboxyl-containing ligands via EDC\/NHS chemistry. \n      The larger micron-scale size makes them particularly suitable for direct microscopic visualization, flow cytometry, phagocytosis assays, and agglutination-based diagnostics. \n      They serve as a versatile platform for creating custom antibody-coated beads, targeted drug-delivery microparticles, and diagnostic reagents.\n    \u003c\/p\u003e\n    \u003cp\u003e\n      Key applications include:\n    \u003c\/p\u003e\n    \u003cul style=\"padding-left:20px;\"\u003e\n      \u003cli\u003eCovalent conjugation of antibodies, proteins, peptides, or dyes\u003c\/li\u003e\n      \u003cli\u003ePhagocytosis and immune cell interaction studies\u003c\/li\u003e\n      \u003cli\u003eImmunoassays and particle-based agglutination tests\u003c\/li\u003e\n      \u003cli\u003eCell labeling and separation techniques\u003c\/li\u003e\n      \u003cli\u003eDevelopment of targeted microparticles for drug delivery or diagnostics\u003c\/li\u003e\n    \u003c\/ul\u003e\n    \n    \u003c!-- USAGE \u0026 HANDLING --\u003e\n    \u003ch3 style=\"margin-top:30px;\"\u003eUsage \u0026amp; Handling Guidance\u003c\/h3\u003e\n    \u003cp\u003e\n      Store at 2–8°C. Do not freeze. Gently vortex or pipette up and down before use to ensure uniform suspension. \n      For conjugation, wash beads if necessary and follow standard EDC\/NHS protocols. After coupling, quench unreacted groups with glycine or ethanolamine.\n    \u003c\/p\u003e\n    \u003cul style=\"padding-left:20px;\"\u003e\n      \u003cli\u003e\n\u003cstrong\u003eTypical working concentration:\u003c\/strong\u003e 0.1–1% (w\/v) for conjugation reactions\u003c\/li\u003e\n      \u003cli\u003e\n\u003cstrong\u003eConjugation chemistry:\u003c\/strong\u003e EDC\/NHS coupling to carboxyl-containing ligands\u003c\/li\u003e\n      \u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for months when stored refrigerated; protect from contamination\u003c\/li\u003e\n    \u003c\/ul\u003e\n    \n    \u003c!-- WHAT YOU GET --\u003e\n    \u003ch3 style=\"margin-top:30px;\"\u003eWhat You Get\u003c\/h3\u003e\n    \u003cul style=\"padding-left:20px;\"\u003e\n      \u003cli\u003e5 mL of Amine-Modified Polystyrene Latex Beads (5.0-5.9 µm, 5% w\/v suspension)\u003c\/li\u003e\n      \u003cli\u003eReactive surface amine groups for easy covalent bioconjugation\u003c\/li\u003e\n      \u003cli\u003eUniform particle size distribution for reproducible results\u003c\/li\u003e\n      \u003cli\u003eConvenient volume for multiple experiments and scale-up\u003c\/li\u003e\n      \u003cli\u003eFor research use only (RUO)\u003c\/li\u003e\n    \u003c\/ul\u003e\n    \n    \u003c!-- WHY RESEARCHERS CHOOSE IT --\u003e\n    \u003ch3 style=\"margin-top:30px;\"\u003eWhy Researchers Choose It\u003c\/h3\u003e\n    \u003cul style=\"padding-left:20px;\"\u003e\n      \u003cli\u003eHigh-density amine surface for efficient covalent conjugation\u003c\/li\u003e\n      \u003cli\u003e5 µm size ideal for microscopy, flow cytometry, and phagocytosis studies\u003c\/li\u003e\n      \u003cli\u003eStable polystyrene core with low non-specific binding\u003c\/li\u003e\n      \u003cli\u003eConvenient 5% w\/v suspension and 5 mL volume for practical lab use\u003c\/li\u003e\n      \u003cli\u003eVersatile platform for custom functionalized microparticles and diagnostics\u003c\/li\u003e\n    \u003c\/ul\u003e\n    \n    \u003c!-- FAQ --\u003e\n    \u003ch3 style=\"margin-top:30px;\"\u003eFrequently Asked Questions (FAQ)\u003c\/h3\u003e\n    \u003cul style=\"padding-left:20px;\"\u003e\n      \u003cli\u003e\n\u003cstrong\u003eWhat chemistry is used for conjugation?\u003c\/strong\u003e\u003cbr\u003e\n        EDC\/NHS coupling to carboxyl groups on proteins, antibodies, or other ligands.\u003c\/li\u003e\n      \u003cli\u003e\n\u003cstrong\u003eCan these beads be used in cell studies?\u003c\/strong\u003e\u003cbr\u003e\n        Yes. The 5 µm size is well-suited for phagocytosis, cell labeling, and interaction assays.\u003c\/li\u003e\n      \u003cli\u003e\n\u003cstrong\u003eHow should I store the product?\u003c\/strong\u003e\u003cbr\u003e\n        Store at 2–8°C. Do not freeze. Mix gently before each use.\u003c\/li\u003e\n      \u003cli\u003e\n\u003cstrong\u003eAre the beads fluorescent?\u003c\/strong\u003e\u003cbr\u003e\n        No. These are plain amine-modified polystyrene beads. Fluorescent versions are available separately.\u003c\/li\u003e\n      \u003cli\u003e\n\u003cstrong\u003eWhat is the particle concentration?\u003c\/strong\u003e\u003cbr\u003e\n        5% (w\/v) suspension. Dilute as needed for your conjugation or assay protocol.\u003c\/li\u003e\n    \u003c\/ul\u003e\n    \n    \u003cdiv style=\"margin-top:20px; font-weight:bold; color:#c8102e;\"\u003e\n      This product is for Research Use Only (RUO). It is not intended for diagnostic or therapeutic use in humans or animals.\n    \u003c\/div\u003e\n    \n    \u003chr\u003e\n    \n   \u003ch4\u003eReferences\u003c\/h4\u003e\n\n\u003cul style=\"padding-left: 0; margin: 0; list-style: none;\"\u003e\n\n  \u003cli style=\"display: flex; justify-content: space-between; align-items: flex-start; gap: 12px; padding: 8px 0; border-bottom: 1px solid #eee;\"\u003e\n    \u003cspan style=\"flex: 1;\"\u003e\n      Banerjee A, Billey LO, Shelver WL. Uptake and toxicity of polystyrene micro\/nanoplastics in gastric cells: Effects of particle size and surface functionalization.\n      \u003cem\u003ePLoS ONE.\u003c\/em\u003e 2021 Dec 31;16(12):e0260803.\n    \u003c\/span\u003e\n    \u003ca href=\"https:\/\/doi.org\/10.1371\/journal.pone.0260803\" target=\"_blank\" style=\"flex-shrink: 0; margin-top: 2px;\"\u003e\n      \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height: 28px; width: auto;\"\u003e\n    \u003c\/a\u003e\n  \u003c\/li\u003e\n\n  \u003cli style=\"display: flex; justify-content: space-between; align-items: flex-start; gap: 12px; padding: 8px 0; border-bottom: 1px solid #eee;\"\u003e\n    \u003cspan style=\"flex: 1;\"\u003e\n      Paget V, Dekali S, Kortulewski T, Grall R, Gamez C, Blazy K, Aguerre-Chariol O, Chevillard S, Braun A, Rat P, Lacroix G. Specific uptake and genotoxicity induced by polystyrene nanobeads with distinct surface chemistry on human lung epithelial cells and macrophages.\n      \u003cem\u003ePLoS ONE.\u003c\/em\u003e 2015 Apr 15;10(4):e0123297.\n    \u003c\/span\u003e\n    \u003ca href=\"https:\/\/doi.org\/10.1371\/journal.pone.0123297\" target=\"_blank\" style=\"flex-shrink: 0; margin-top: 2px;\"\u003e\n      \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height: 28px; width: auto;\"\u003e\n    \u003c\/a\u003e\n  \u003c\/li\u003e\n\n  \u003cli style=\"display: flex; justify-content: space-between; align-items: flex-start; gap: 12px; padding: 8px 0; border-bottom: 1px solid #eee;\"\u003e\n    \u003cspan style=\"flex: 1;\"\u003e\n      Jeon S, Clavadetscher J, Lee DK, Chankeshwara SV, Bradley M, Cho WS. Surface charge-dependent cellular uptake of polystyrene nanoparticles.\n      \u003cem\u003eNanomaterials (Basel).\u003c\/em\u003e 2018 Dec 10;8(12):1028.\n    \u003c\/span\u003e\n    \u003ca href=\"https:\/\/doi.org\/10.3390\/nano8121028\" target=\"_blank\" style=\"flex-shrink: 0; margin-top: 2px;\"\u003e\n      \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height: 28px; width: auto;\"\u003e\n    \u003c\/a\u003e\n  \u003c\/li\u003e\n\n  \u003cli style=\"display: flex; justify-content: space-between; align-items: flex-start; gap: 12px; padding: 8px 0; border-bottom: 1px solid #eee;\"\u003e\n    \u003cspan style=\"flex: 1;\"\u003e\n      Zhang F, Wang Z, Wang S, Fang H, Wang D. Aquatic behavior and toxicity of polystyrene nanoplastic particles with different functional groups: Complex roles of pH, dissolved organic carbon and divalent cations.\n      \u003cem\u003eChemosphere.\u003c\/em\u003e 2019 Aug;228:195-203.\n    \u003c\/span\u003e\n    \u003ca href=\"https:\/\/doi.org\/10.1016\/j.chemosphere.2019.04.115\" target=\"_blank\" style=\"flex-shrink: 0; margin-top: 2px;\"\u003e\n      \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height: 28px; width: auto;\"\u003e\n    \u003c\/a\u003e\n  \u003c\/li\u003e\n\n  \u003cli style=\"display: flex; justify-content: space-between; align-items: flex-start; gap: 12px; padding: 8px 0; border-bottom: 1px solid #eee;\"\u003e\n    \u003cspan style=\"flex: 1;\"\u003e\n      Siiman O, Burshteyn A, Insausti ME. Covalently bound antibody on polystyrene latex beads: Formation, stability, and use in analyses of white blood cell populations.\n      \u003cem\u003eJ Colloid Interface Sci.\u003c\/em\u003e 2001 Feb 1;234(1):44-58.\n    \u003c\/span\u003e\n    \u003ca href=\"https:\/\/doi.org\/10.1006\/jcis.2000.7279\" target=\"_blank\" style=\"flex-shrink: 0; margin-top: 2px;\"\u003e\n      \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height: 28px; width: auto;\"\u003e\n    \u003c\/a\u003e\n  \u003c\/li\u003e\n\n  \u003cli style=\"display: flex; justify-content: space-between; align-items: flex-start; gap: 12px; padding: 8px 0; border-bottom: 1px solid #eee;\"\u003e\n    \u003cspan style=\"flex: 1;\"\u003e\n      Ercan MT, Tuncel SA, Caner BE, Pişkin E. 99mTc-labelled monodisperse latex particles coated with amino or carboxyl groups for studies of GI function.\n      \u003cem\u003eJ Microencapsul.\u003c\/em\u003e 1993 Jan-Mar;10(1):67-76.\n    \u003c\/span\u003e\n    \u003ca href=\"https:\/\/doi.org\/10.3109\/02652049309015313\" target=\"_blank\" style=\"flex-shrink: 0; margin-top: 2px;\"\u003e\n      \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height: 28px; width: auto;\"\u003e\n    \u003c\/a\u003e\n  \u003c\/li\u003e\n\n  \u003cli style=\"display: flex; justify-content: space-between; align-items: flex-start; gap: 12px; padding: 8px 0; border-bottom: 1px solid #eee;\"\u003e\n    \u003cspan style=\"flex: 1;\"\u003e\n      Cho YS, Ji S, Kim YS. Synthesis of polymeric nanoparticles by emulsion polymerization for particle self-assembly applications.\n      \u003cem\u003eJ Nanosci Nanotechnol.\u003c\/em\u003e 2019 Oct 1;19(10):6398-6407.\n    \u003c\/span\u003e\n    \u003ca href=\"https:\/\/doi.org\/10.1166\/jnn.2019.17032\" target=\"_blank\" style=\"flex-shrink: 0; margin-top: 2px;\"\u003e\n      \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height: 28px; width: auto;\"\u003e\n    \u003c\/a\u003e\n  \u003c\/li\u003e\n\n  \u003cli style=\"display: flex; justify-content: space-between; align-items: flex-start; gap: 12px; padding: 8px 0; border-bottom: 1px solid #eee;\"\u003e\n    \u003cspan style=\"flex: 1;\"\u003e\n      Kaur H, Kumar S, Kukkar D, Kaur I, Singh K, Bharadwaj LM. Transportation of drug-(polystyrene bead) conjugate by actomyosin motor system.\n      \u003cem\u003eJ Biomed Nanotechnol.\u003c\/em\u003e 2010 Jun;6(3):279-86.\n    \u003c\/span\u003e\n    \u003ca href=\"https:\/\/doi.org\/10.1166\/jbn.2010.1124\" target=\"_blank\" style=\"flex-shrink: 0; margin-top: 2px;\"\u003e\n      \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/Reference.png?v=1775409336\" alt=\"Reference\" style=\"height: 28px; width: auto;\"\u003e\n    \u003c\/a\u003e\n  \u003c\/li\u003e\n\n  \u003cli style=\"display: flex; justify-content: space-between; align-items: flex-start; gap: 12px; padding: 8px 0; border-bottom: 1px solid #eee;\"\u003e\n    \u003cspan style=\"flex: 1;\"\u003e\n      Seamster PE, Loewenberg M, Pascal J, Chauviere A, Gonzales A, Cristini V, Bearer EL. Quantitative measurements and modeling of cargo-motor interactions during fast transport in the living axon.\n      \u003cem\u003ePhys Biol.\u003c\/em\u003e 2012 Oct;9(5):055005.\n  \u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Molecular Depot","offers":[{"title":"Default Title","offer_id":51510059172138,"sku":"B2025677","price":1295.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/B2025677-600x539.png?v=1778180224","url":"https:\/\/bluetigerscientific.com\/products\/amine-modified-polystyrene-latex-beads-5-0-5-9-um-5-w-v-research-use-only-non-medical","provider":"Blue Tiger Scientific","version":"1.0","type":"link"}