{"product_id":"alexa-fluor-647-conjugated-to-mouse-igg1-isotype","title":"Alexa Fluor 647 Conjugated to Mouse IgG1, κ Isotype","description":"\u003cdiv style=\"max-width: 1400px; margin: 0 auto; padding: 40px 20px; font-family: 'Open Sans', sans-serif; font-weight: 300; background: #fff; color: #333; font-size: 0.95rem; box-sizing: border-box;\"\u003e\n                                    \u003cdiv style=\"display: flex; flex-direction: column; gap: 20px;\"\u003e\n                                        \u003cp\u003e\u003cstrong\u003eAlexa Fluor 647 Conjugated to Mouse IgG1, κ Isotype\u003c\/strong\u003e\u003c\/p\u003e\n                                        \u003cdiv style=\"overflow-x: auto; max-width: 100%; margin-bottom: 20px;\"\u003e\n                                        \u003ctable style=\"width: 500px; border-collapse: collapse;\"\u003e\n                                            \u003ctbody\u003e\n                                            \u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eCatalog number:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e B2016003\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eLot number:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Batch Dependent\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eExpiration Date:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Batch dependent\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eAmount:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e 25 µg\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eMolecular Weight or Concentration:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e N\/A\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eSupplied as:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Solution\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e a molecular tool for various biochemical applications\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e -20 °C\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eKeywords:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Mouse IgG1, κ Isotype\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n\u003ctr style=\"border-bottom: 1px solid #ddd;\"\u003e\n                                        \u003ctd style=\"width: 150px; padding-right: 10px;\"\u003e\u003cstrong\u003eGrade:\u003c\/strong\u003e\u003c\/td\u003e\n                                        \u003ctd style=\"width: 350px;\"\u003e Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity \u0026gt;18 MΩ-cm) and are filtered through 0.22 um.\u003c\/td\u003e\n                                        \u003c\/tr\u003e\n                                            \u003c\/tbody\u003e\n                                        \u003c\/table\u003e\n                                        \u003c\/div\u003e\n\n                                        \u003chr\u003e\n                                        \u003ch4\u003eReferences\u003c\/h4\u003e\n                                        \n                \u003cul style=\"padding-left: 20px; margin: 0;\"\u003e\n                \u003cli\u003eZhai Y, Dong S, Li H, Zhang Y, Shami P, Chen M. Antibody-mediated depletion of programmed death 1-positive (PD-1(+)) cells J Control Release. 2022 Sep;349:425-433.\u003c\/li\u003e\n\u003cli\u003eSordillo EM, Pearse RN. RANK-Fc: a therapeutic antagonist for RANK-L in myeloma Cancer. 2003 Feb 1;97(3 Suppl):802-12.\u003c\/li\u003e\n\u003cli\u003eHu XX, Zhang AJ, Pan WW, Xin QL, Chen JY, Zhang LL, Chang Y, Wu YJ, Wei W. An IgD-Fc-Ig fusion protein restrains the activation of T and B cells by inhibiting IgD-IgDR-Lck signaling in rheumatoid arthritis Acta Pharmacol Sin. 2022 Feb;43(2):387-400.\u003c\/li\u003e\n\u003cli\u003eBranstetter E, Duff RJ, Kuhns S, Padaki R. Fc glycan sialylation of biotherapeutic monoclonal antibodies has limited impact on antibody-dependent cellular cytotoxicity FEBS Open Bio. 2021 Nov;11(11):2943-2949.\u003c\/li\u003e\n\u003cli\u003eMerz C, Sykora J, Marschall V, Richards DM, Heinonen K, Redondo Müller M, Thiemann M, Schnyder T, Fricke H, Hill O, Gieffers C. The Hexavalent CD40 Agonist HERA-CD40L Induces T-Cell-mediated Antitumor Immune Response Through Activation of Antigen-presenting Cells J Immunother. 2018 Nov\/Dec;41(9):385-398.\u003c\/li\u003e\n\u003cli\u003eWilson NS, Yang B, Yang A, Loeser S, Marsters S, Lawrence D, Li Y, Pitti R, Totpal K, Yee S, Ross S, Vernes JM, Lu Y, Adams C, Offringa R, Kelley B, Hymowitz S, Daniel D, Meng G, Ashkenazi A. An Fcγ receptor-dependent mechanism drives antibody-mediated target-receptor signaling in cancer cells Cancer Cell. 2011 Jan 18;19(1):101-13.\u003c\/li\u003e\n\u003cli\u003eMiller RE, Branstetter D, Armstrong A, Kennedy B, Jones J, Cowan L, Bussiere J, Dougall WC. Receptor activator of NF-kappa B ligand inhibition suppresses bone resorption and hypercalcemia but does not affect host immune responses to influenza infection J Immunol. 2007 Jul 1;179(1):266-74.\u003c\/li\u003e\n\u003cli\u003eDegn SE, Andersen SH, Jensen L, Thiel S, Jensenius JC. Assay interference caused by antibodies reacting with rat kappa light-chain in human sera J Immunol Methods. 2011 Sep 30;372(1-2):204-8.\u003c\/li\u003e\n\u003cli\u003eAdriaansen J, Khoury M, de Cortie CJ, Fallaux FJ, Bigey P, Scherman D, Gould DJ, Chernajovsky Y, Apparailly F, Jorgensen C, Vervoordeldonk MJ, Tak PP. Reduction of arthritis following intra-articular administration of an adeno-associated virus serotype 5 expressing a disease-inducible TNF-blocking agent Ann Rheum Dis. 2007 Sep;66(9):1143-50.\u003c\/li\u003e\n                \u003c\/ul\u003e\n                                    \u003c\/div\u003e\n                                \u003c\/div\u003e","brand":"Molecular Depot","offers":[{"title":"Default Title","offer_id":50478271037738,"sku":"BTS-B2016003","price":795.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0896\/1579\/4474\/files\/B2016003.png?v=1754869639","url":"https:\/\/bluetigerscientific.com\/products\/alexa-fluor-647-conjugated-to-mouse-igg1-isotype","provider":"Blue Tiger Scientific","version":"1.0","type":"link"}