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EGFR (Domain III) Chimeric Monoclonal Antibody Antibodies Molecular Depot
EGFR (Domain III) Chimeric Monoclonal Antibody Antibodies Molecular Depot
EGFR (Domain III) Chimeric Monoclonal Antibody Antibodies Molecular Depot
EGFR (Domain III) Chimeric Monoclonal Antibody Antibodies Molecular Depot

EGFR (Domain III) Chimeric Monoclonal Antibody

$995.00

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What's Included

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VR Headset

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2 Touch Controllers

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Charging Cable

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Power Adapter

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Glasses Spacer

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EGFR (Domain III) Chimeric Monoclonal Antibody

Catalog number: B2017767
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Epidermal Growth Factor Receptor, ErbB-1, HER1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References

  • Greenall SA, McKenzie M, Seminova E, Dolezal O, Pearce L, Bentley J, Kuchibhotla M, Chen SC, McDonald KL, Kornblum HI, Endersby R, Adams TE, Johns TG. Most clinical anti-EGFR antibodies do not neutralize both wtEGFR and EGFRvIII activation in glioma Neuro Oncol. 2019 Aug 5;21(8):1016-1027.
  • Leung K. 4-[(18)F]Fluorobenzoyl-Phe-Ala-Leu-Gly-Glu-Ala-NH(2) 2011 Aug 26 [updated 2011 Dec 8]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013.
  • Luedke E, Jaime-Ramirez AC, Bhave N, Carson WE 3rd. Monoclonal antibody therapy of pancreatic cancer with cetuximab: potential for immune modulation J Immunother. 2012 Jun;35(5):367-73.
  • Thokala R, Binder ZA, Yin Y, Zhang L, Zhang JV, Zhang DY, Milone MC, Ming GL, Song H, O’Rourke DM. High-Affinity Chimeric Antigen Receptor With Cross-Reactive scFv to Clinically Relevant EGFR Oncogenic Isoforms Front Oncol. 2021 Sep 10;11:664236.
  • Jiang H, Gao H, Kong J, Song B, Wang P, Shi B, Wang H, Li Z. Selective Targeting of Glioblastoma with EGFRvIII/EGFR Bitargeted Chimeric Antigen Receptor T Cell Cancer Immunol Res. 2018 Nov;6(11):1314-1326.
  • Chopra A. [(177)Lu]-Labeled α-(5-isothiocyanato-2-methoxyphenyl)-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (MeO-DOTA) conjugated monoclonal antibody L8A4 against epidermal growth factor receptor variant III (EGFRvIII) 2010 Dec 24 [updated 2011 Feb 17]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013.
  • Chopra A. [(177)Lu]-Labeled [(R)-2-amino-3-(4-isothiocyanatophenyl)propyl]-trans-(S,S)-cyclohexane-1,2-diamine-pentaacetic acid (CHX-A″-DTPA) conjugated monoclonal antibody L8A4 against epidermal growth factor receptor variant III (EGFRvIII) 2010 Dec 24 [updated 2011 Feb 17]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013.
  • Xiao Q, Li X, Li Y, Wu Z, Xu C, Chen Z, He W. Biological drug and drug delivery-mediated immunotherapy Acta Pharm Sin B. 2021 Apr;11(4):941-960.
  • Mazzarella L, Guida A, Curigliano G. Cetuximab for treating non-small cell lung cancer Expert Opin Biol Ther. 2018 Apr;18(4):483-493.

Product Resources:

Manual Manual
Brochure Brochure

Copy of Technical Specifications

FeatureDetails
Viewing Head Siedentopf type trinocular head, inclined at 30°, Interpupillary adjustment 53mm to 75mm, graduated diopter on left eyetube (30mm I.D. eyetubes)
Eyepieces SWH10X Widefield high eyepoint eyepiece, Field No. 22, tube O.D. 30.0 mm
Nosepiece Quintuple
Quintuple LWD Planachromat Phase 10x, 20x
Condenser TC Condenser N.A. 0.30, W.D. 73.0mm
Stage180mm(X) x 245mm(Y) plain stage with replaceable glass insert with 45mm opening, Glass Stage plate insert
IlluminationKoehler without iris, with phase slider, 3W LED
WarrantyLIMITED LIFETIME WARRANTY

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